{"count":250,"next":null,"previous":"https://memento.epfl.ch/api/v1/events/?format=json&limit=10&offset=230&ordering=event__speaker","results":[{"id":71326,"title":"Camp Océan - Sailowtech","slug":"camp-ocean-sailowtech","event_url":"https://memento.epfl.ch/event/camp-ocean-sailowtech","visual_url":"https://memento.epfl.ch/image/32680/200x112.jpg","visual_large_url":"https://memento.epfl.ch/image/32680/720x405.jpg","visual_maxsize_url":"https://memento.epfl.ch/image/32680/max-size.jpg","lang":"en","start_date":"2026-04-25","end_date":"2026-04-25","start_time":"13:30:00","end_time":"15:30:00","description":"<p>This event is free and open to everyone. It aims to raise awareness of various issues concerning the ocean through workshops, exhibitions, conferences, and a roundtable discussion. 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We uncovered a new mechanism for coincidence detection in the Drosophila head direction network. To maintain an accurate sense of direction, head direction neurons that signal orientation during navigation must learn to anchor to relevant external sensory cues in novel environments. Yet the synaptic mechanism for this form of unsupervised learning is unknown in any organism. In Drosophila, GABAergic visual inputs converge onto head direction neurons, and these inhibitory synapses change strength with experience to learn the relationship between visual landmarks and head direction. However, how coincident pre- and postsynaptic activity is detected across this inhibitory synapse is not understood. We discovered that neurons which release the monoamine octopamine close a feedback loop that conveys postsynaptic head direction activity onto presynaptic terminals of visual inputs. This octopamine pathway is required for anchoring the head direction network to visual cues. Furthermore, pairing structured activation of octopamine neurons with a visual cue is sufficient to drive rapid plasticity, even without postsynaptic head direction cell activity. 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