retrieve:
Return the details about the given Memento id.

list:
List all Memento objects.

GET /api/v1/mementos/6/events/?format=api&offset=60&ordering=fr_name
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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            "id": 71342,
            "title": "lunch&LEARN: AI for formative feedback. From effective tools to adoption",
            "slug": "lunchlearn-ai-for-formative-feedback-from-effectiv",
            "event_url": "https://memento.epfl.ch/event/lunchlearn-ai-for-formative-feedback-from-effectiv",
            "visual_url": "https://memento.epfl.ch/image/32696/200x112.jpg",
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            "start_date": "2026-04-30",
            "end_date": "2026-04-30",
            "start_time": "12:15:00",
            "end_time": "13:00:00",
            "description": "<p>We can build the perfect pedagogical tool. But will students actually use and benefit from it?<br>\r\n<br>\r\nThis session explores a question at the heart of the integration of new technology into education: How can a well-designed pedagogical tool be ideally leveraged to truly make a difference in student learning?<br>\r\n<br>\r\n<a href=\"https://people.epfl.ch/fares.fawzi?lang=en\">Fares Fawzi</a> from the <a href=\"https://www.epfl.ch/labs/ml4ed/\">ML4ED</a> lab at EPFL will present his development of a GenAI-powered formative feedback tool that is pedagogically aligned, contextually grounded, and interactive.<br>\r\n<br>\r\nDeployed during an in-class session as well as for exam preparation in a computer science course at EPFL, the tool performed as intended: responses were relevant, accurate, and aligned with pedagogical frameworks for feedback delivery.<br>\r\n<br>\r\nHowever, during this session, we want to invite you to look beyond the pedagogical sophistication of the tool itself, and ask how integration context shapes student engagement and beneficial learning impact.<br>\r\n<br>\r\n- - - - - - - - - - - - - <br>\r\n<br>\r\n<em><strong>lunch&amp;LEARN</strong></em> sessions are intended for anyone who teaches at EPFL. <br>\r\nThis session is hybrid and can be attended in person or <a href=\"https://epfl.zoom.us/meeting/register/itgbPQceSnyGQK_-KbEttA\">followed via zoom</a>.<br>\r\nMost sessions are recorded and can be found on the <a href=\"https://www.youtube.com/playlist?list=PLKZOhx3xKAdI81PA1jwBA_LHHfSjbdEUV\">Center LEARN's YouTube channel</a>.<br>\r\nTo get in touch with the team, to suggest a session or make inquiries, please send an email on <a href=\"mailto:[email protected]\">[email protected]</a></p>",
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            "creation_date": "2026-03-10T14:13:42",
            "last_modification_date": "2026-03-10T14:18:13",
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            "speaker": "<a href=\"https://people.epfl.ch/fares.fawzi?lang=en\">Fares Fawzi</a>, Machine Learning for Education Laboratory ",
            "organizer": "<a href=\"https://learn.epfl.ch\">Center LEARN</a>",
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            "id": 70990,
            "title": "\"Mapping the Human Body One Cell at a Time.\"",
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            "start_date": "2026-04-30",
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            "description": "<strong>A Lola and John Grace Distinguished Lecture in Cancer Research</strong>\r\n<div class=\"elementor-element elementor-element-98cefd8 elementor-widget elementor-widget-heading\">\r\n<div class=\"elementor-widget-container\"><br>\r\nSarah Teichmann completed her PhD at the MRC Laboratory of Molecular Biology in Cambridge, UK, and was a Beit Memorial Fellow at University College London. She established her research group at the MRC Laboratory of Molecular Biology in 2001, where her main discoveries included the finding that protein assembly pathways are stereotypical and conserved. In 2013, she transitioned to the Wellcome Genome Campus, where she became the first and, to date, the only faculty member appointed across both the EMBL-European Bioinformatics Institute and the Wellcome Sanger Institute. In 2016, she was appointed as the Head of the Cellular Genetics programme at the Wellcome Sanger Institute and co-founded the Human Cell Atlas initiative. From April 2024, she was appointed chair in Stem Cell Medicine at the University of Cambridge, within the Department of Medicine and the Cambridge Stem Cell Institute. Additionally, Sarah dedicates part of her time to GlaxoSmithKline and to EnsoCell Therapeutics, the startup company she co-founded. The Teichmann lab focuses on developing and applying cell atlas technologies to understand human tissue architecture, particularly examining how cellular diversity is generated in the immune system and during development.</div>\r\n</div>\r\n\r\n<div class=\"elementor-element elementor-element-e552a16 elementor-widget elementor-widget-text-editor\">\r\n<div class=\"elementor-widget-container\"> </div>\r\n</div>",
            "image_description": "",
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            "link_label": "",
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            "speaker": "<strong>Sarah Teichmann FMedSci FRS</strong> (Group Leader), Cambridge Stem Cell Institute &amp; Department of Medicine, Jeffrey Cheah Biomedical Centre, University of Cambridge",
            "organizer": "Prof. Charlotte Bunne",
            "contact": "Lisa Smith, ISREC Administrative Assistant",
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            "theme": "",
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            "keywords": "Grace Lecture, cancer",
            "file": null,
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        {
            "id": 71495,
            "title": "Reprogramming GPCR Specificity: Engineering CXCR2 for Selective CXCL5 Binding and Cellular Signaling",
            "slug": "reprogramming-gpcr-specificity-engineering-cxcr2-2",
            "event_url": "https://memento.epfl.ch/event/reprogramming-gpcr-specificity-engineering-cxcr2-2",
            "visual_url": "https://memento.epfl.ch/image/32837/200x112.jpg",
            "visual_large_url": "https://memento.epfl.ch/image/32837/720x405.jpg",
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            "lang": "en",
            "start_date": "2026-04-30",
            "end_date": "2026-04-30",
            "start_time": "17:00:00",
            "end_time": null,
            "description": "<p>Thesis Director: Prof. P. D. Barth,<br>\r\nBiotechnology and Bioengineering doctoral program<br>\r\nThesis Nr. 11393<br>\r\n<br>\r\nTo take part in the public defense, please contact directly the speaker</p>",
            "image_description": "",
            "creation_date": "2026-03-30T16:59:07",
            "last_modification_date": "2026-03-30T16:59:08",
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            "speaker": "<strong>Ana Paola RICO VILLARREAL</strong>",
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            "id": 70418,
            "title": "7 habits to free up your time",
            "slug": "7-habits-to-free-up-your-time-8",
            "event_url": "https://memento.epfl.ch/event/7-habits-to-free-up-your-time-8",
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            "start_date": "2026-04-30",
            "end_date": "2026-05-18",
            "start_time": "08:30:00",
            "end_time": "12:55:00",
            "description": "<ul>\r\n\t<li>Discover and cure your 4 time management viruses</li>\r\n\t<li>Help the person to set up a personal organization that brings him a lasting balance in life</li>\r\n\t<li>Be more attentive to their needs and satisfy them • Have concrete &amp; practical tools for managing emotions that alter judgment and the decision-making process</li>\r\n\t<li>Differentiate the management of priorities and emergencies</li>\r\n\t<li>Gain autonomy and take responsibility for achieving your goals</li>\r\n\t<li>Connect their knowledge of neuroscience</li>\r\n</ul>\r\nDuration: 3 half-days",
            "image_description": "",
            "creation_date": "2025-11-12T21:27:03",
            "last_modification_date": "2025-11-12T21:35:53",
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            "speaker": "Michelangelo Pilato",
            "organizer": "KeepLearning",
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        {
            "id": 71604,
            "title": "CDM-MTEI Seminars: Performance Optimization Programming: Methodology, Algorithms and Insights",
            "slug": "cdm-mtei-seminars-performance-optimization-program",
            "event_url": "https://memento.epfl.ch/event/cdm-mtei-seminars-performance-optimization-program",
            "visual_url": "https://memento.epfl.ch/image/32936/200x112.jpg",
            "visual_large_url": "https://memento.epfl.ch/image/32936/720x405.jpg",
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            "lang": "en",
            "start_date": "2026-05-01",
            "end_date": "2026-05-01",
            "start_time": "11:30:00",
            "end_time": "13:00:00",
            "description": "<strong>Abstract</strong>:<br>\r\nThe design of efficient optimization algorithms has long relied on intuition and hand-crafted analysis. A newer paradigm -- Performance Optimization Programming (POP) -- reframes the question of algorithm analysis as a metaoptimization problem, enabling a computer-assisted, systematic search for optimal methods. We introduce Branch-and-Bound Performance Estimation Programming (BnB-PEP), a unified methodology for constructing certifiably optimal first-order methods for both convex and nonconvex optimization. Prior PEP-based approaches formulate worst-case performance as a convex semidefinite program, but this convexity is simultaneously a limitation: only a narrow class of problem setups admit such tractable reformulations. BnB-PEP overcomes this barrier by directly embracing nonconvexity. BnB-PEP is applied to several settings that were previously intractable: constructing the optimal gradient method without momentum, deriving optimal methods for reducing gradient norms of smooth nonconvex functions, and designing efficient methods for weakly convex nonsmooth optimization. In each case, the methodology yields new state-of-the-art convergence bounds. Finally, we show how the analysis generalizes to settings with gradient corruption and allows for the discovery of an entirely novel class of first-order optimization algorithms which enjoy optimal corruption protection.<br>\r\n<br>\r\n<br>\r\n<strong>References:</strong>\r\n<ul>\r\n\t<li>[Das Gupta, van Parys, Ryu: Branch-and-Bound Performance Estimation Programming](<a href=\"https://arxiv.org/pdf/2203.07305\">https://arxiv.org/pdf/2203.07305</a>)</li>\r\n\t<li>[Gösgens, van Parys: Subgradient Methods for Nonsmooth Convex Functions with Adversarial Errors](<a href=\"https://arxiv.org/abs/2510.03072\">https://arxiv.org/abs/2510.03072</a>)</li>\r\n</ul>\r\n<br>\r\n<br>\r\n<strong>Short bio: Bart van Parys</strong> is a senior researcher in the Stochastics groupt at the Dutch National Institute for Mathematics and Computer Science (CWI). Bart has played a pioneering role in developing distributionally robust optimization (DRO) as a practical tool for decision-making in uncertain environments. His doctoral work pioneered DRO formulations in stochastic control theory and power systems. Key innovations were an extension of the inequality of Gauss from 1821 in terms of tractable convex optimization problems.<br>\r\nMore recently, Bart formalized the search for statistically efficient data-driven decisions by advancing a novel meta-optimization framework via large-deviations theory. Bart's current research is primarily methodological and revolves around fundamental concerns when making decisions based on wild data sets and the automated design of better optimization algorithms.<br>\r\n ",
            "image_description": "",
            "creation_date": "2026-04-15T18:05:10",
            "last_modification_date": "2026-04-15T18:05:10",
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                "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api"
            ],
            "speaker": "Professor Bart VAN PARYS\r\n\r\nDutch National Institute for Mathematics and Computer Science (CWI)",
            "organizer": "Prof. Daniel Kuhn",
            "contact": "[email protected]",
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            "file": null,
            "icalendar_url": "https://memento.epfl.ch/event/export/120394/",
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                "https://memento.epfl.ch/api/v1/mementos/27/?format=api",
                "https://memento.epfl.ch/api/v1/mementos/38/?format=api"
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        {
            "id": 71574,
            "title": "Entropy methods and nonlinear flows for symmetry and stability results",
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            "event_url": "https://memento.epfl.ch/event/entropy-methods-and-nonlinear-flows-for-symmetry-a",
            "visual_url": "https://memento.epfl.ch/image/32910/200x112.jpg",
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            "lang": "en",
            "start_date": "2026-05-01",
            "end_date": "2026-05-01",
            "start_time": "14:15:00",
            "end_time": null,
            "description": "<strong>Abstract</strong><br>\r\nThe lecture will be based on entropy methods for nonlinear diffusion equations with two main goals: 1. A review of various results of symmetry for the optimizers of nonlinear interpolation inequalities and a classification of some phase transitions between symmetry and symmetry breaking regimes; 2. Constructive methods for stability results in functional inequalities, including explicit results à la Bianchi-Egnell for Sobolev, log-Sobolev and related functional inequalities. Most of these results are based on a nonlinear carré du champ method.",
            "image_description": "",
            "creation_date": "2026-04-12T18:11:57",
            "last_modification_date": "2026-04-13T11:52:07",
            "link_label": "",
            "link_url": "",
            "canceled": "False",
            "cancel_reason": "",
            "place_and_room": "MA B1 11",
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            "speaker": "<strong>Pof. Jean Dolbeault</strong> (Paris Dauphine University – France)",
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            "contact": "B. Buffoni, SMA",
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            "id": 70157,
            "title": "Innovate with AI and Tech",
            "slug": "innovate-with-ai-and-tech-4",
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            "start_date": "2026-05-04",
            "end_date": "2026-05-08",
            "start_time": null,
            "end_time": null,
            "description": "<strong>Drive growth with new technologies</strong><br>\r\n<br>\r\nEPFL &amp; IMD join forces to offer you a unique learning experience to drive innovation with game-changing technologies like AI, IoT, and robotics.<br>\r\n<br>\r\nNew technologies can greatly enhance your business value, enabling you to develop fresh products and services, boost productivity and save time. However, in a rapidly evolving field, how do you identify which tech solutions offer you the best opportunities to innovate and grow?<br>\r\n<br>\r\nThis 5-day program brings together business and technology experts to help you identify your most promising strategic opportunities using innovative technologies like AI, robotics, and quantum computing. You’ll leverage AI as your innovation partner, enhancing how you develop and validate solutions. You’ll cultivate an innovator’s mindset, gaining cutting-edge knowledge, skills, and the confidence to make impactful technology decisions.<br>\r\n<br>\r\nInnovate with AI and Tech is a must for leaders and managers in all business areas looking to leverage new technologies to drive faster innovation and growth.",
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            "last_modification_date": "2026-03-30T10:10:26",
            "link_label": "Website",
            "link_url": "https://www.imd.org/digital-transformation/iait/innovate-ai-technologies/",
            "canceled": "False",
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                "en_label": "Registration required"
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            "keywords": "Innovation, AI",
            "file": null,
            "icalendar_url": "https://memento.epfl.ch/event/export/118202/",
            "category": {
                "id": 4,
                "code": "DIVERS",
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                "en_label": "Miscellaneous",
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        },
        {
            "id": 71541,
            "title": "Les Culturelles (Cultural Week) 2026",
            "slug": "les-culturelles-cultural-week-2026",
            "event_url": "https://memento.epfl.ch/event/les-culturelles-cultural-week-2026",
            "visual_url": "https://memento.epfl.ch/image/32879/200x112.jpg",
            "visual_large_url": "https://memento.epfl.ch/image/32879/720x405.jpg",
            "visual_maxsize_url": "https://memento.epfl.ch/image/32879/max-size.jpg",
            "lang": "en",
            "start_date": "2026-05-04",
            "end_date": "2026-05-11",
            "start_time": "12:00:00",
            "end_time": "20:00:00",
            "description": "<strong>Arts, Sciences, and Perspectives on the World</strong><br>\r\n<br>\r\nTwice a year, the Pôle Culture presents Les Culturelles (<a href=\"https://www.epfl.ch/campus/art-culture/les-culturelles-cultural-week/\">Cultural Week</a>), a festival that explores contemporary issues through the arts. The May 2026 edition features performances, films, music, dance, exhibitions, and guided tours.<br>\r\n<br>\r\nMicroorganisms, root systems, and lake landscapes inspire artists and researchers. Lake Geneva becomes a cyborg organism, an iconic sculpture is reborn on screen, Chopin resonates under the fingers of students, while others create a surrealist film or an improvised performance. A tour by Archizoom traces the history of the School of Architecture, and a choreographed walk invites visitors to experience the campus in a new light.<br>\r\n<br>\r\nLes Culturelles offers a sensory and reflective experience, where art dialogues with science and opens up new imaginaries.<br>\r\n<br>\r\n<strong>May 2026 Program (chronological order - prgram in French)</strong><br>\r\n<br>\r\n<strong>Monday 4 May</strong><br>\r\n<a href=\"https://memento.epfl.ch/event/moto-etude-de-mouvement-concert-performance/\"><em>MOTO</em> </a>– Concert-performance, 12:00, Hall MED<br>\r\n<a href=\"https://memento.epfl.ch/event/bleue-saignante-exposition-et-film/\"><em>Bleue Saignante</em></a> – Vernissage, 18:30, Foyer SG<br>\r\n<br>\r\n<strong>Tuesday 5 May</strong><br>\r\n<a href=\"https://memento.epfl.ch/event/dncity-2026-performance/\"><em>DÆNCITY 2026</em></a> – Performance, 12:00, Hall SG<br>\r\n<a href=\"https://memento.epfl.ch/event/visite-guidee-de-deux-expositions/\">Visite guidée Archizoom</a> – 17:30, SG <br>\r\n<em>Bleue Saignante</em> – Film, 19:30, Forum RLC<br>\r\n<br>\r\n<strong>Wednesday 6 May</strong><br>\r\n<a href=\"https://memento.epfl.ch/event/de-en-bulle-promenade-sante/\"><em>Dé-en-bulle</em></a> – Promenade chorégraphique, 09:00<br>\r\n<br>\r\n<strong>Thursday 7 May</strong><br>\r\n<a href=\"https://memento.epfl.ch/event/le-leman-cyborg-performance/\"><em>Le Léman Cyborg</em></a> – Performance, 12:00, Hall SG<br>\r\n<a href=\"https://memento.epfl.ch/event/unearthed-rahel-oberhummer/\"><em>Unearthed</em> </a>– Vernissage, 18:30, SG (expo until 11 October 2026)<br>\r\n<br>\r\n<strong>Saturday 9 May</strong><br>\r\n<a href=\"https://memento.epfl.ch/event/concours-chopin-etudiante-concert/\">Concours Chopin Étudiant·e – Finale</a>, 16:30, Forum RLC<br>\r\n<br>\r\n<strong>Monday 11 May</strong><br>\r\n<a href=\"https://memento.epfl.ch/event/a-laune-danse-et-projection/\"><em>À l’aune</em></a> – Danse, 12:00, Place Ada Lovelace<br>\r\n<a href=\"https://memento.epfl.ch/event/piscine-une-video-de-marion-baeriswyl-et-dcp/\">Projection de la vidéo <em>Piscine</em></a> – 12:00–15:00, Foyer SG<br>\r\n<a href=\"https://memento.epfl.ch/event/element-blanc-film-et-discussion-2/\"><em>Élément blanc</em></a> – Film &amp; discussion, 18:30, Forum RLC",
            "image_description": "",
            "creation_date": "2026-04-14T12:12:10",
            "last_modification_date": "2026-04-14T12:31:27",
            "link_label": "Les Culturelles 2026",
            "link_url": "https://www.epfl.ch/campus/art-culture/fr/les-culturelles/",
            "canceled": "False",
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            "place_and_room": "EPFL Campus",
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            "contact": "<a href=\"mailto:[email protected]\">Véronique Mauron Layaz</a>",
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                "fr_label": "Entrée libre",
                "en_label": "Free"
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            "keywords": "",
            "file": null,
            "icalendar_url": "https://memento.epfl.ch/event/export/120370/",
            "category": {
                "id": 9,
                "code": "MANIF",
                "fr_label": "Événements festifs et culturels",
                "en_label": "Cultural events",
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        },
        {
            "id": 71568,
            "title": "AI Center x Anthropic Impact Talk - Jonah Cool - \"AI for Science at Anthropic: Building Tools for Scientific Discovery\"",
            "slug": "ai-center-x-anthropic-impact-talk-jonah-cool-ai--2",
            "event_url": "https://memento.epfl.ch/event/ai-center-x-anthropic-impact-talk-jonah-cool-ai--2",
            "visual_url": "https://memento.epfl.ch/image/32904/200x112.jpg",
            "visual_large_url": "https://memento.epfl.ch/image/32904/720x405.jpg",
            "visual_maxsize_url": "https://memento.epfl.ch/image/32904/max-size.jpg",
            "lang": "en",
            "start_date": "2026-05-05",
            "end_date": "2026-05-05",
            "start_time": "14:30:00",
            "end_time": "15:30:00",
            "description": "<p>The talk is jointly organized by the <a href=\"https://ai.epfl.ch/\">EPFL AI Center</a> and the <a href=\"https://aimm.epfl.ch\">AIMM</a> Lab as part of the AI for Science seminar series.<br>\r\n<br>\r\n<strong><em>Hosting professor: Prof. Charlotte Bunne (AIMM)</em></strong><br>\r\n<br>\r\n<em><strong>Registration with an EPFL email is required: <a href=\"https://forms.office.com/e/F0PALJFN3D\">HERE</a>.</strong></em><br>\r\n<br>\r\n<u><strong>! This event is restricted to EPFL members. The Zoom live stream is also restricted and requires authentication with an EPFL email address for access. !</strong></u><br>\r\n<br>\r\n<strong>Title</strong><br>\r\nAI for Science at Anthropic: Building Tools for Scientific Discovery<br>\r\n<br>\r\n<strong>Abstract</strong><br>\r\nThis talk will explore Anthropic's approach to developing AI systems that can meaningfully accelerate scientific research. I'll discuss our AI for Science program, share examples of how researchers are using Claude across domains from molecular biology to materials science, and outline our thinking on what makes AI genuinely useful for working scientists. I'll also touch on the Model Context Protocol (MCP) and how it enables integration with scientific tools and data sources.<br>\r\n<br>\r\n<strong>Bio</strong><br>\r\nJonah Cool leads life sciences partnerships and deployment at Anthropic, where he works directly with researchers, academic institutions, and biotech startups to apply frontier AI to scientific discovery. His focus is on understanding where large language models can meaningfully accelerate biological research and building the partnerships, evaluation frameworks, and deployment practices to make that happen responsibly.<br>\r\n<br>\r\nBefore Anthropic, Jonah served as VP of Science &amp; Partnerships at the Chan Zuckerberg Initiative, where he launched the Single Cell Biology program and led cross-sector technology development spanning biotech, academia, and philanthropy. He holds a PhD in cell biology (AHA fellow) and completed a postdoctoral fellowship at the Salk Institute (NIH fellow). His career has moved across academia, biotech startups, large-scale philanthropy, and now frontier AI, connected by a consistent focus on finding the leverage points where new technology can change how science gets done.</p>",
            "image_description": "",
            "creation_date": "2026-04-10T10:19:48",
            "last_modification_date": "2026-04-15T10:24:18",
            "link_label": "Registration required (epfl.ch email address only)",
            "link_url": "https://forms.office.com/e/F0PALJFN3D",
            "canceled": "False",
            "cancel_reason": "",
            "place_and_room": "SV 1717",
            "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717",
            "url_online_room": "https://epfl.zoom.us/j/63663088641?pwd=R57BacyioFy78i0vZ7o8IYH6I5duKA.1",
            "spoken_languages": [
                "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api"
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            "speaker": "Jonah Cool, PhD",
            "organizer": "<a href=\"http://ai.epfl.ch\">EPFL AI Center,</a> <a href=\"https://aimm.epfl.ch/\">EPFL AIMM Lab</a>",
            "contact": "<a href=\"https://people.epfl.ch/nicolas.machado?lang=en\">Nicolas Machado</a>",
            "is_internal": "True",
            "theme": "",
            "vulgarization": {
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                "fr_label": "Public averti",
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                "fr_label": "Sur inscription",
                "en_label": "Registration required"
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            "keywords": "",
            "file": null,
            "icalendar_url": "https://memento.epfl.ch/event/export/120338/",
            "category": {
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                "code": "CONF",
                "fr_label": "Conférences - Séminaires",
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                "https://memento.epfl.ch/api/v1/mementos/6/?format=api",
                "https://memento.epfl.ch/api/v1/mementos/8/?format=api",
                "https://memento.epfl.ch/api/v1/mementos/9/?format=api",
                "https://memento.epfl.ch/api/v1/mementos/27/?format=api"
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        },
        {
            "id": 70233,
            "title": "Cryo electron microscopy of vitreous sections revisited for high throughput tomographic imaging of tissue and cells",
            "slug": "cryo-electron-microscopy-of-vitreous-sections-revi",
            "event_url": "https://memento.epfl.ch/event/cryo-electron-microscopy-of-vitreous-sections-revi",
            "visual_url": "https://memento.epfl.ch/image/31688/200x112.jpg",
            "visual_large_url": "https://memento.epfl.ch/image/31688/720x405.jpg",
            "visual_maxsize_url": "https://memento.epfl.ch/image/31688/max-size.jpg",
            "lang": "en",
            "start_date": "2026-05-05",
            "end_date": "2026-05-05",
            "start_time": "16:00:00",
            "end_time": "17:00:00",
            "description": "<br>\r\n<br>\r\nCellular cryo electron tomography is experiencing spectacular developments, revealing with increasing resolution and complexity the structures and interactions of macromolecules at work in living matter. To obtain thin samples from biological tissue and cells in their flash-frozen native state, cryo-FIB milling is nowadays the most popular method, with impressive successes. The alternative, cryo-ultramicrotomy - also known as CEMOVIS - has been overshadowed because of (i) technical difficulties associated to cryo-section generation and collection - in particular the lack of control over adhesion; and (ii) crevasses and compression artefacts.<br>\r\nI will present recent developments with optimization of the experimental workflow, focusing on section adhesion and their support grids. These result in high throughput data acquisition, with typically several tens to hundreds of cryo-tomograms per sample. Revisiting cutting artefacts shows that crevasses alter but 10 % of the sample volume. Compression is heterogeneous, with scale and material-dependent effects. This is altogether a drawback – with no simple computational correction – and an advantage for projects dedicated to non-(or little)-affected objects such as nucleosomes and chromatin.<br>\r\nAltogether, it is time to revive CEMOVIS as a practical alternative to cryo-FIB milling, offering specific advantages: (i) imaging of large areas of any type of sample, from cells to tissues, organs or even entire organisms – and more generally all kinds of hydrated molecular systems ; (ii) the possibility of serial section approaches ; (iii) no beam damage ; and (iv) a specimen thickness that can be tuned down to 30-50 nm, which may be an advantage for high resolution imaging of small molecular complexes.<br>\r\n<br>\r\n<br>\r\n<br>\r\n<br>\r\n<strong>Biography</strong><br>\r\n<br>\r\nAmélie Leforestier is a CNRS research director at the Solid-State Physics Laboratory (LPS, Paris-Saclay, France). After a PhD in Life Sciences on liquid crystalline self-assembly of DNA, she learned cryo electron microscopy during her post-doctoral studies in the group of Jacques Dubochet in Lausanne. Back in France, she set up a cryo-EM facility for soft matter physics at LPS. She is part of an <a href=\"https://equipes.lps.u-psud.fr/sobio/\">interdisciplinary team</a> dedicated to self-assembly processes at work in living systems at the molecular level. Her work, combining concepts from soft matter physics (poly-electrolytes, liquid crystals, frustration) and structural biology, focuses on the geometry and interactions in condensed states of DNA and chromosomes <em>in vitro</em> and <em>in situ</em>.",
            "image_description": "",
            "creation_date": "2025-10-29T08:00:54",
            "last_modification_date": "2026-03-04T11:07:41",
            "link_label": "",
            "link_url": "",
            "canceled": "False",
            "cancel_reason": "",
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            "url_online_room": "https://epfl.zoom.us/j/65708791562",
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            "speaker": "Amélie Leforestier | CNRS, France",
            "organizer": "CIME",
            "contact": "[email protected]",
            "is_internal": "True",
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            },
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                "fr_label": "Entrée libre",
                "en_label": "Free"
            },
            "keywords": "",
            "file": null,
            "icalendar_url": "https://memento.epfl.ch/event/export/118314/",
            "category": {
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                "en_label": "Conferences - Seminars",
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