WEBINAR - BMI Progress Reports 2020 // Prof. Petersen's Lab: Keita Tamura
Event details
| Date | 29.04.2020 |
| Hour | 12:15 › 13:00 |
| Speaker | Keita Tamura, Laboratory of Sensory Processing |
| Category | Conferences - Seminars |
Learning-induced changes in sensory-motor processing in mouse dorsal cortex
We update our behavior by learning values of sensory inputs, but the neural mechanisms remain to be understood. I trained mice to detect a whisker stimulus and lick for a reward after one second of a delay period. Wide-field calcium imaging of dorsal cortex revealed that the whisker stimulation evoked a series of activation and deactivation of different cortical areas only in expert mice, suggesting learning-induced transformation of whisker sensory input into licking motor output. To investigate potential circuit changes, I have begun to combine wide-field imaging with optogenetic manipulation. Measuring causal interactions among cortical regions will reveal how learning remodels cortical circuits.
We update our behavior by learning values of sensory inputs, but the neural mechanisms remain to be understood. I trained mice to detect a whisker stimulus and lick for a reward after one second of a delay period. Wide-field calcium imaging of dorsal cortex revealed that the whisker stimulation evoked a series of activation and deactivation of different cortical areas only in expert mice, suggesting learning-induced transformation of whisker sensory input into licking motor output. To investigate potential circuit changes, I have begun to combine wide-field imaging with optogenetic manipulation. Measuring causal interactions among cortical regions will reveal how learning remodels cortical circuits.
Practical information
- Informed public
- Free
Organizer
- Brain Mind Institute