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SUMMARY:Toward a renewed understanding of host defenses against microbial 
 infections in Drosophila
DTSTART:20211210T100000
DTEND:20211210T110000
DTSTAMP:20260428T230552Z
UID:8384645de8e8eb0ac49f2b3bbea0a947c8902337fdb0208019787899
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dominique Ferrandon\nDrosophila melanogaster is a potent genet
 ic model to investigate host defenses against infections and to decipher m
 echanisms of innate immunity. The current paradigm is that upon the sensin
 g of infectious microbes present in the internal body cavity of the fly\, 
 the NF-kB-type signal transduction pathways Toll and Immune deficiency are
  activated in the fat body and lead to the release in the hemolymph of mul
 tiple secreted peptides\, many of which have been shown to act as antimicr
 obial peptides.\nWe are interested in the study of fungal infections in th
 is model\, which are controlled\, to a large extent\, by Toll-regulated im
 mune processes. Our work leads us to reconsider our current understanding 
 of the host response to systemic infections by ascribing unexpected functi
 ons for several effectors of the Toll pathway\, thereby opening novel venu
 es for investigating immune defenses against microbial infections.\n\n-> A
 I 1153: masks & COVID pass requested\n-> Zoom password: Droso
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153 https://epfl.zoom.u
 s/j/62781050384?pwd=UWJsRERnR3czSWpob01sZk9wZWtOQT09
STATUS:CONFIRMED
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