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SUMMARY:Engineering organoids for the testing of rare bone marrow stromal 
 cell populations
DTSTART:20211216T121500
DTEND:20211216T131500
DTSTAMP:20260929T061136Z
UID:6c5cbb78c7fee0ecf280c9e2e0a41c13c2ab73f8d98fb766b4000623
CATEGORIES:Conferences - Seminars
DESCRIPTION:Martin Ehrbar\, Head of Research\, Department of Obstetrics\, 
 University Hospital Zurich\nThe bone marrow (BM) is an intricate and tight
 ly regulated organ\, home to hematopoietic stem and progenitor cells (HSPC
 s) as well as bone marrow stromal cells (BMSCs) that sustain the body’s 
 hematopoietic system and drive connective tissue regeneration. Recent find
 ings indicate that BMSCs are a heterogeneous\, not fully defined cell popu
 lation comprising\, among others\, minor fractions of skeletal stem cells.
  To decipher the function of low abundant BMSC populations\, there is a gr
 eat need to develop tailorable in vitro and in vivo models. I will pre
 sent the engineering of bone and bone marrow organoid models using a modul
 ar designed poly(ethylene glycol) PEG-based hydrogel. I will show how we m
 ake use of these models to characterize human BMSCs in vivo. Finally\, I 
 will give an insight into our ongoing research activities on the refinemen
 t of our current models towards their use in a multiplexing format for the
  testing and manipulation of rare bone marrow stromal cell populations.\n\
 n-> Hosting unit: Deplancke lab\n-> SV 1717: masks & COVID pass requested\
 n-> Zoom passcode: 1372
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/61240655168?pwd=K3crd2VqeVoyOWRuUGdXL1hxNzlvdz09
STATUS:CONFIRMED
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