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SUMMARY:CIBM Breakfast and Science Seminars
DTSTART:20220628T090000
DTEND:20220628T103000
DTSTAMP:20260407T163629Z
UID:7bd4d51e0c52ccde7ab38c23eb27dd5d11c960d0b81a0b7aacdf3345
CATEGORIES:Conferences - Seminars
DESCRIPTION:Since April 2019\, Priscille Guerrier de Dumast is pursuing he
 r PhD thesis focusing on the development of an integrated reconstruction-s
 egmentation framework for T2w fetal brain imaging\, along with the explora
 tion of novel segmentation method to allow quantitative analysis of high-r
 esolution 3D images. The thesis is under supervision of Dr. Meritxell Bach
  Cuadra with the support of Swiss National Science Foundation (SNSF-205321
 _182602).\n\nSince February 2020\, Mark Widmaier is an EDEE PhD student at
  EPFL. He is currently working on the acceleration of 31P MRS in human bra
 in using magnetic resonance fingerprinting. The thesis is under supervisio
 n of Prof. Rolf Gruetter and Lijing Xin with the support of Swiss National
  Science Foundation (SNSF- 320030_189064).\n\n\n\n\n\n\n\nDeep learning me
 thods for fetal brain MRI tissue segmentation\nPriscille Guerrier de Dumas
 t\, MIAL UNIL & CIBM SP CHUV-UNIL\nThe quantitative assessment of the deve
 loping human brain in utero is crucial to fully understand neurodevelopmen
 t. T2-weighted magnetic resonance imaging offers a good contrast between b
 rain tissues\, hence allowing to assess the brain growth and detect abnorm
 alities in utero. In the clinical context\, fetal brain MRI is performed w
 ith fast\, 2D orthogonal series in order to minimize the effect of unpredi
 ctable fetal motion but results in low out-of-plane spatial resolution and
  significant partial volume effect. To combine these multiple series\, adv
 anced imaging techniques based on super-resolution (SR) algorithms allow t
 he reconstruction of 3D high-resolution motion-free isotropic volumes. Suc
 h high-resolution volume opens up to the possibility of advanced quantitat
 ive analysis of improved accuracy. Accurate MR image segmentation\, and mo
 re importantly a topologically correct delineation of the structure\, is a
  key baseline to perform further morphometric and volumetric analysis of b
 rain development. Nevertheless\, the development of automatic machine lear
 ning based methods is hampered by the scarcity of the data and their multi
 ple sources of variability. In this talk\, I will discuss my work on the i
 ntroduction of a topological constraint in the segmentation of the develop
 ing fetal cortical plate.\n\nFast in vivo assay of creatine kinase in huma
 n brain by 31P magnetic resonance fingerprinting\nMark Widmaier\, LIFMET E
 PFL & CIBM MRI EPFL\n31P MRS is a powerful tool for studying brain energy 
 metabolism\, however\, it remains a challenging task. Especially\, relaxom
 etry and chemical exchange rates acquisitions\, suffer from the inherent l
 ow sensitivity and long acquisition times.  We introduce MT- 31P magnetic
  resonance fingerprinting\, using a SAR efficient magnetization transfer (
 MT) approach. We extended the magnet resonance fingerprinting (MRF) framew
 ork to overcome obstacles of in vivo human brain 31P measurements. The res
 ult is an efficient way to measure relaxation parameters and the creatine 
 kinase rate kCK\, enabling ultra-fast kCK measurement in up to 2:15 min sc
 an time. This talk will give a short journey into the challenges and possi
 bilities of 31P-MRF. \n\n\n\n\n\n\n
LOCATION:CIBM Seminar room https://epfl.zoom.us/w/63086100836?tk=ARWX-2uxr
 wZF0bgj6laYt3oLzE7vUH-8q6-XjvSKaNg.DQMAAAAOsDmBZBZDbGFHUFhrYVF4T3N3dl9vZHh
 3ZEVBAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA https://cibm.ch/events/breakfast-scien
 ce-seminars/
STATUS:CONFIRMED
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