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SUMMARY:AdEC Seminars -  Topology and Molecular Machines : Two Interlinked
  Research Fields
DTSTART:20220323T170000
DTEND:20220323T190000
DTSTAMP:20260928T223458Z
UID:9dfb5e2f7502ce8af75300d7821e3da18d6bfdcdd27f412c7ffc3b02
CATEGORIES:Conferences - Seminars
DESCRIPTION:Pr. Jean-Pierre Sauvage\nWe are very delighted to announce you
  the next AdEC seminar in which we will be hosting a very special guest\, 
 Professor Jean-Pierre Sauvage\, laureate of the 2016 Nobel Prize alongside
  James Fraser Stoddart and Bernard L. Feringa. Professor Sauvage\, a forme
 r CNRS researcher and member of l’Académie des Sciences has been reward
 ed for his pioneering work in the design and synthesis of molecular machin
 es.\n\nThis seminar will be happening on Zoom Wednesday 23rd of March beg
 inning from 17:00. The seminar will begin first with a talk from Professor
  Sauvage before pursuing with a questions and answers session.\n\nAbstract
 \n\nThe area referred to as "Chemical Topology" is mostly concerned with m
 olecules whose molecular graph is non-planar\, i.e. which cannot be repres
 ented in a plane without crossing points. The most important family of suc
 h compounds is that of catenanes. The simplest catenane\, a [2]catenane\, 
 consists of two interlocking rings. Rotaxanes consist of rings threaded by
  acyclic fragments (axes). These compounds have always been associated to 
 catenanes although\, strictly speaking\, their molecular graphs are planar
 . Knotted rings are more challenging to prepare. Several spectacular knott
 ed topologies at the molecular level have been created since the beginning
  of the 90s either by our group or by other highly creative research teams
 .\n\nSince the mid-90s\, the field of artificial molecular machines has ex
 perienced a spectacular development\, in relation to molecular devices at 
 the nanometric level or as mimics of biological motors. In biology\, motor
  proteins are of utmost importance in a large variety of processes essenti
 al to life (ATP synthase\, a rotary motor\, or the myosin-actin complex of
  striated muscles behaving as a linear motor responsible for contraction o
 r elongation). Many examples published by a large number of highly creativ
 e research groups are based on complex rotaxanes or catenanes acting as sw
 itchable systems or molecular machines. Particularly significant examples 
 include a “pirouetting catenane”\, “molecular shuttles” (Stoddart 
 and others) as well as multi-rotaxanes reminiscent of muscles. More recent
  examples are those of multi-rotaxanes able to behave as compressors and s
 witchable receptors or as molecular pumps. The molecules are set in motion
  using electrochemical\, photonic or chemical signals. Particularly impres
 sive light-driven rotary motors have been created by the team of Feringa.\
 nFinally\, potential applications will be mentioned as well as possible fu
 ture developments of this active area of research.
LOCATION:https://epfl.zoom.us/j/66975046998?pwd=bzEwaUlOdU15T21zSEgrbjdjYX
 lhQT09
STATUS:CONFIRMED
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