BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:EPFL BioE Talks SERIES "Advancing In Vitro Pulmonary Platforms fo r Inhalation Assays" DTSTART:20220321T160000 DTEND:20220321T170000 DTSTAMP:20260929T053359Z UID:077e256eaf6a776b8eaea63edf5c727842d16ace4cd0f10ebbebf82e CATEGORIES:Conferences - Seminars DESCRIPTION:Prof. Josué Sznitman\, Department of Biomedical Engineering\, Technion – Israel Institute of Technology\, Haifa (IL)\nWEEKLY EPFL BIO E TALKS SERIES\n\nAbstract:\nOver the past years\, advanced in vitro pulmo nary platforms have witnessed exciting developments that are pushing beyon d traditional preclinical cell culture methods. Here\, we discuss ongoing efforts in bridging the gap between in vivo and in vitro interfaces and id entify some of the bioengineering challenges that lie ahead in delivering new generations of human-relevant in vitro pulmonary platforms. Undeniably \, there still remains a recognized trade-off between the physiological an d biological complexity of in vitro lung models and exemplify various mode ls developed in our group. With growing interest in aerosol transmission a nd infection of respiratory viruses within a host\, most notably the SARS- CoV-2 virus amidst the global COVID-19 pandemic\, the importance of crosst alk between the different lung regions (i.e. extra-thoracic\, conductive a nd respiratory)\, with distinct cellular makeups and physiology\, are ackn owledged to play an important role in the progression of the disease from the initial onset of infection. We showcase to the best of our knowledge t he first multi-compartment human airway-on-chip platform to serve as a pre clinical in vitro benchmark underlining regional lung crosstalk for viral infection pathways.\n\nBio:\nJosué Sznitman is a Swiss\, French and Israe li national. Sznitman graduated from MIT with a BSc in Mechanical Engineer ing (2002)\, followed by a Dr. Sc. (2008) from the ETH Zurich. In 2008\, S znitman joined the University of Pennsylvania as a Postdoctoral Fellow and moved to Princeton University as a Lecturer and Research Associate\, appo inted by the Princeton Council of Science & Technology. He joined the Tech nion in October 2010 as a tenure-track Assistant Professor and was promote d to Associate Professor with tenure in 2016. Sznitman’s research unders cores respiratory transport phenomena and pulmonary physiology\, with a fo cus on preclinical models and drug delivery to the lungs including inhalat ion therapy. He is an associate editor for the Journal of Biomechanics\, C linical Biomechanics and Frontiers in Bioengineering & Biotechnology and a lso serves as a member of the Editorial Board of Biomicrofluidics and the European Journal of Pharmaceutical Sciences. Among his accolades\, Sznitma n was awarded the Young Investigator Award (2015) by the International Soc iety of Aerosols in Medicine (ISAM) for a researcher under 40 and most rec ently the 2018 Emerging Scientist Award in Drug Delivery to the Lungs (The Aerosol Society\, UK). His recent dissemination activities have included Webinars and the opportunity to deliver a TEDx Talk (2019) titled “From race cars to the lungs”. \n\n\n\nZoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioET alks\n\n\nInstructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:\nIF you are not attending in-person in the room\, please make sure to\n\n send D. Reinhard a note before noon on seminar day\, informing that you plan to attend the talk online\, and\n be signed in on Zoom with a recognizable user name (not a pseudonym making i t difficult or impossible to be identified).\n\nStudents attending the sem inar in-person should collect a confirmation signature after the talk - pl ease print your own signature sheet beforehand (71 kB pdf available for do wnload here). LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/ EPFLBioETalks STATUS:CONFIRMED END:VEVENT END:VCALENDAR