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SUMMARY:Biomaterials and technologies for highly biomimetic organ and tiss
 ue models
DTSTART:20220504T140000
DTEND:20220504T150000
DTSTAMP:20261002T084706Z
UID:dabc9026f833b9ce7c939a9991aeef0c3066f7e2ee2c8dc2bd0aec32
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Gianluca Ciardelli\,\nPolitecnico di Torino\, Italy\nAbs
 tract:\nDespite its being around for more than 50 years\, Tissue Engineeri
 ng has brought little commercial translation\, with only few products havi
 ng achieved market success. However\, the increased understanding of human
  biology and our capacity to replicate it through sophisticated technologi
 es and tailor-made materials has stimulated optimistic market forecasts.\n
 The design of 3D replicas of living tissues is expected to gain increasing
  attention considering their potential in personalized medicine and in hig
 h-throughput testing of cosmetics\, drugs and chemicals\, where they contr
 ibute to reduce animal experiments. It is worth considering e.g. that ~75%
  of drugs approved for liver and cardiac pathologies are withdrawn from th
 e market due to safety concerns which were not highlighted in pre-clinical
  testing. Moreover\, bioengineered models represent a more realistic scena
 rio for the testing of implantable devices (e.g.\, prostheses testing in b
 one models).\nAd-hoc designed materials are expected to play a strategic r
 ole in this arena\, since they recapitulate the multicomponent composition
  and complex architecture of the native extracellular matrix (ECM).\nDespi
 te this potential\, new biomaterials are still under-exploited: for instan
 ce\, polyesterurethanes are extremely promising as cardiac patches but the
 ir difficult pathway to FDA approval negatively affected their translation
 .\nThe talk will focus on novel trends in materials design\, functionaliza
 tion\, and processing into biomimetic structures for the development of ex
 perimental models that respond to current challenges in the testing and ev
 aluation of chemicals\, drugs\, and implantable devices.\n\nBio:\nGianluca
  Ciardelli has a PhD in Natural Sciences (ETH Zurich). He has been assista
 nt professor (University of Pisa) then Professor at Politecnico di Torino 
 (Full Professor since 2011) and coordinates a group of around 15 researche
 rs in the biomedical polymers field. He has been appointed as Chair of the
  Conference of the European Society of Biomaterials (2025). He is Editoria
 l Board member for  “nanomaterials” and “Journal of Healthcare Engi
 neering”. He has acted as external expert assisting\, a.o.\, REA\, ESF\,
  Eurostars. He published over 150 articles in peer-reviewed journals\, 8 b
 ook chapters\; 12 patents. H-index is 43 (over 7000 SCOPUS citations).\n 
LOCATION:BM 5202 https://plan.epfl.ch/?room==BM%205202 https://epfl.zoom.u
 s/j/67588035845
STATUS:CONFIRMED
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