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SUMMARY:U.S. DOD CDMRP - Peer Reviewed Alzheimer’s Disease Research Prog
 ram
DTSTART;VALUE=DATE:20220617
DTSTAMP:20260504T152646Z
UID:86c13cd190cea8f54605224a3a6e2b0120f9d4a40655ec5d082a1822
CATEGORIES:Call for proposal
DESCRIPTION:Through the Congressionally Directed Medical Research Program 
 (CDMRP)\, the Department of Defense is announcing the Peer Reviewed Alzhei
 mer’s Disease Research Program (PRARP). Three award programs are availab
 le:\n\n	The Translational Research Award support translational research th
 at will accelerate the movement of promising products and knowledge in Alz
 heimer’s disease (AD) / AD-related dementias (ADRD) research into clinic
 al applications\, including healthcare products and interventions\, techno
 logies\, behavioral modalities\, social modalities\, and/or clinical pract
 ice guidelines. This mechanism supports both preclinical-to-clinical trans
 lational research (e.g.\, studies of interventions and medical devices in 
 preclinical systems) and clinical research-to-clinical care translation (e
 .g.\, comparative effectiveness\, implementation science\, healthcare serv
 ices research).\n	 \n	The FY22 Investigator- Initiated Research Award sup
 ports studies that will make important contributions to TBI and/or militar
 y-service-related factors as they pertain to AD/ADRD research\, patient ca
 re\, and quality of life. The work should innovatively challenge existing 
 paradigms or exhibit high levels of creativity. Applications may focus on 
 any phase of research from basic through translational. The program encour
 ages applications that include meaningful and productive collaborations be
 tween investigators.\n	 \n	The FY22 Accelerating Diagnostics Research Awa
 rd support high-impact advancement of robust diagnostic and/or prognostic 
 factors pertaining to AD/ADRD following military service and/or TBI. Appli
 cations meeting the intent of this mechanism will accelerate clinically us
 eful factors for rapid transfer to clinical practice to bridge a critical 
 gap between identification of relevant factors and clinical usage. The pro
 posed factors for investigation must correlate with clinical endpoints rel
 evant to AD/ADRD following military service and/or traumatic brain injury.
 \n\n\nAREAS OF INTEREST\nTo address the intent of the award mechanism\, ap
 plications submitted to this program announcement must address at least on
 e of the Focus Areas:\n\n	Individual\, caregiver\, and family support:\n	D
 iagnostic\, environmental\, and prognostic factors\n	Foundational science 
 to improve understanding of the mechanisms\, etiology\, comorbidities\, th
 erapeutics/treatments\n\n\nDEADLINE:\n\n\n	FY22 Translational Research Awa
 rd - Pre-Application (1 page limit): June 17\, 2022\, submission on July 2
 5\, 2022\n	FY22 Investigator- Initiated Research Award - Pre-Application (
 1 page limit): June 17\, 2022\, submission on July 25\, 2022\n	FY22 Accele
 rating Diagnostics Research Award - Pre-Application (1 page limit): June 1
 7\, 2022\, submission on July 25\, 2022\n\n\nFUNDING:\n\n\n	FY22 Translati
 onal Research Award - Anticipated total costs will not exceed $1.2M for a 
 maximum of 4 years period of performance\n	FY22 Investigator- Initiated Re
 search Award - Anticipated total costs will not exceed $750\,000 for 3 yea
 rs period of performance\n	FY22 Accelerating Diagnostics Research Award - 
 Anticipated total costs will not exceed $2.5M for 4 years period of perfor
 mance\n\n\nELIGIBILITY: EPFL researchers are eligible to participate.\n\nH
 OW TO APPLY: Pre-applications are submitted through the eBRAP platform. Fu
 ll applications will be made via a Grants.gov workspace. Full application 
 packages can be downloaded from Grants.gov at any time.\n\nFOR FURTHER INF
 ORMATION: Please refer to the FOAs below and feel free to contact the Rese
 arch Office for any question or any help.\n\n\n	FY22 Translational Researc
 h Award - W81XWH-22-PRARP-TRA\n	FY22 Investigator- Initiated Research Awar
 d - W81XWH-22-PRARP-IIRA\n	FY22 Accelerating Diagnostics Research Award - 
 W81XWH-22-PRARP-ADRA\n
LOCATION:
STATUS:CONFIRMED
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