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SUMMARY:Mitochondria and Monoamines - Better Together
DTSTART:20220705T163000
DTEND:20220705T173000
DTSTAMP:20260511T081216Z
UID:44af9b90d5bca6fbdae43d102fa49f73cc242608b03cf0efacd9fcde
CATEGORIES:Conferences - Seminars
DESCRIPTION:Vidita Vaidya\, Department of Biological Sciences\, Tata Insti
 tute of Fundamental Research\, India\nMonoamines\, phylogenetically ancie
 nt molecules that predates the evolution of the nervous system\, were like
 ly co-opted to function as neurotransmitters. Monoamines retain “pre-ne
 rvous” trophic-factor actions influencing development and growth\, whils
 t exerting pleiotropic neurotransmitter effects on diverse brain functions
  and behavior. In my talk I will discuss our results about the influence o
 f the monoamines\, serotonin and norepinephrine on the energy producing or
 ganelle\, mitochondria\, and on a neuron’s stress buffering capacity. M
 itochondria have recently emerged as important targets to consider both fr
 om the perspective of pathogenesis and treatment of psychiatric disorders.
  Mitochondria contribute to the buffering of stress-associated allostatic 
 load\, and mitochondrial dysfunction can hamper stress-adaptation and enha
 nce risk for psychopathology. In this regard the influence of monoaminergi
 c pathways on mitochondrial biogenesis and functions has broad ranging imp
 lications for both understanding pathophysiological mechanisms and target
 s for therapy of relevance for neurodegenerative and neuropsychiatric dise
 ases.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/66731694578?pwd=emk4ekdiVU01Q2ZDdU9sZGJGalVyUT09
STATUS:CONFIRMED
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