BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:US DOD CDMRP - Kidney Cancer Research Program DTSTART;VALUE=DATE:20220617 DTSTAMP:20260407T101346Z UID:36e10f21f1c55e6b37064038c631922dcd11aa929eb893bb2def4421 CATEGORIES:Call for proposal DESCRIPTION:Through the Congressionally Directed Medical Research Program (CDMRP)\, the Department of Defense is announcing the Kidney Cancer Resear ch Program (KCRP) Awards. Four award programs are available:\n \n\n The F Y22 Concept Award supports highly innovative\, untested\, potentially grou ndbreaking novel concepts in kidney cancer. The Concept Award is not inten ded to support an incremental progression of an already established resear ch project but\, instead\, it allows Principal Investigators (PIs) the opp ortunity to pursue serendipitous observations. Preliminary data are not al lowed and should not be discussed. This award mechanism supports high-risk studies that have the potential to reveal entirely new avenues for invest igation. Applications must describe how the new idea will enhance the exis ting knowledge of kidney cancer or develop an innovative and novel course of investigation. Research completed through a Concept Award may generate sufficient preliminary data to enable the PI to prepare an application for future research.\n FY22 Postdoctoral and Clinical Fellowship Award suppor ts recent doctoral or medical school graduates in pursuit of innovative\, high-impact kidney cancer research during their postdoctoral and/or clinic al fellowship and allows them to obtain the necessary experience for an in dependent career as a leader in kidney cancer research. Applicants must de monstrate that the proposed research has high potential to lead to\, or ma ke\, significant advancements in kidney cancer research and/or patient car e. Applicants for this award must also exhibit a strong desire to pursue a career in kidney cancer research\, with clear evidence for a researcher d evelopment plan that will lead to a successful independent career in kidne y cancer.\n FY22 Translational Research Partnership Award supports partner ships between clinicians and research scientists that will accelerate the movement of promising ideas in kidney cancer toward clinical applications. This award supports the development of translational research collaborati ons between two independent\, faculty-level (or equivalent) investigators to address a central problem or question in kidney cancer in a manner that would be less readily achievable through separate efforts. One partner in the collaboration must be a research scientist and the other must be a cl inician.\n FY22 Idea Development Award s intended to support innovative id eas and highimpact approaches\, based on scientifically sound evidence\, t o move toward the KCRP vision of eliminating kidney cancer. The research p roject should include a well-formulated\, testable hypothesis based on str ong scientific rationale and a well-developed and articulated research app roach. Personnel on the proposed team should have a strong background in k idney cancer research.\n\n\nAREAS OF INTEREST (Concept and Idea Developmen t Award)\n\nThe KCRP Focus Areas are presented below:\nConduct basic biolo gy research to better understand etiology and cancer progression\, metasta tic disease\, refractory disease and therapeutic resistance\, genetic and environmental risk factors\, and the prevention of kidney cancer.\n• Def ine the biology of rare kidney cancers and develop treatments to improve o utcomes and reduce death.\n• Identify and develop new strategies for scr eening\, early-stage detection\, and accurate diagnosis and prognosis pred iction of kidney cancers\, with examples including biomarkers and imaging. \n• Develop novel therapeutic strategies for the treatment of kidney can cer\, such as novel drug targets\, therapeutic modalities and agents\, tre atment combinations and drug delivery systems.\n• Identify and implement strategies to improve the quality of life and survivorship for patients.\ n• Identify and implement strategies to mitigate health disparities\, su ch as access to healthcare\, social and cultural factors\, environmental f actors\, and biological contributors.\n• Support preparation and develop ment of the next generation of kidney cancer researchers\, or cultivate co llaborations in kidney cancer research or patient care in alignment with t he KCRP Overarching Strategic Goals.\n\nDEADLINE:\n\n\n FY22 Concept Award - Pre-Application (1 page limit): June 23\, 2022\, submission on July 14\ , 2022\n FY22 Postdoctoral and Clinical Fellowship Award - Pre-Application (1 page limit): June 23\, 2022\, submission on July 19\, 2022\n FY22 Tran slational Research Partnership Award - Pre-Application (two-pages limit fo r the narrative part plus biosketch and reference): June 2\, 2022\, submis sion on Oct 6\, 2022\n FY22 Idea Development Award - Pre-Application (two- pages limit for the narrative part plus biosketch and reference): June 2\, 2022\, submission on Oct 6\, 2022\n\n\nFUNDING:\n\n\n FY22 Concept Award - Anticipated direct costs will not exceed $100\,000 for a maximum of 1 ye ar period of performance\n FY22 Postdoctoral and Clinical Fellowship Award - Anticipated direct costs will not exceed $195\,000 for a maximum of 3 y ears period of performance\n FY22 Translational Research Partnership Award - Anticipated direct costs will not exceed $750\,000 for a maximum of 3 y ears period of performance\n FY22 Idea Development Award - Anticipated dir ect costs will not exceed $675\,000 for a maximum of 3 years period of per formance\n \n Idea Development Award with Early Detection Studies Option: Maximum of $700’000 for 3 years\n Idea Development Award with Populati on Science and Prevention Studies Option: Maximum of $2M for 4 years\n \n \n\n\nELIGIBILITY: EPFL researchers are eligible. For the Concept Award an d PCFA\, researchers at the level of postdoctoral fellow (or equivalent) c an participate.\nHOW TO APPLY: Pre-applications are submitted through the eBRAP platform. Full applications will be made via a Grants.gov workspace. Full application packages can be downloaded from Grants.gov at any time.\ nFOR FURTHER INFORMATION: Please refer to the FOAs below and feel free to contact the Research Office for any question or any help.\n\n\n FY22 Conce pt Award - W81XWH-22-KCRP-CA\n FY22 Postdoctoral and Clinical Fellowship A ward - W81XWH-22-KCRP-PCFA\n FY22 Translational Research Partnership Award - W81XWH-22-KCRP-TRPA\n FY22 Idea Development Award - W81XWH-22-KCRP-IDA\ n\n\n\n\n  LOCATION: STATUS:CONFIRMED END:VEVENT END:VCALENDAR