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SUMMARY:MechE Colloquium: Biomedical microrobots: The quest for utmost rea
 ch and precision
DTSTART:20221011T120000
DTEND:20221011T130000
DTSTAMP:20260502T063940Z
UID:a873109909d21bd1458ee10c11bee23febbda4320bf07bfdd6c332ae
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Mahmut Selman Sakar\, MicroBioRobotic Systems Laboratory
  (MICROBS)\, Institute of Mechanical Engineering (IGM)\, School of Enginee
 ring (STI)\, EPFL\nAbstract: All types of cells\, even bacteria\, demonstr
 ate social behaviors. They engage in communication\, resource sharing\, an
 d construction of higher order structures such as biofilms and tissues. Un
 like engineered systems where components are expected to perform the same 
 in isolation\, tissue cultures possess emergent properties that cannot be 
 deduced from single cell studies. Our group has been developing microrobot
 ic manipulation tools that are integrated with automated microscopes to pe
 rform microsurgical operations\, and apply spatiotemporally resolved force
 s within living tissues. In tandem with time-lapse imaging and computation
 al mechanics\, our toolkit allows us to deconstruct tissue morphogenesis i
 n embryonic development and cancer\, and discover mechanobiological princi
 ples to engineer designer tissues and create synthetic biological machines
 . I will argue that the overall methodology can be applied to study biolog
 ical organization across scales and kingdoms by giving examples from socia
 l insects. Complimentary to these efforts\, we invented a microrobotic tec
 hnology that provides safe and rapid access for slender instruments to dee
 p-seated tissues inside living animals via the endovascular path. I will s
 ummarize our efforts to translate this technology into the clinic for the 
 monitoring of diagnostic signals and targeted delivery of therapeutic agen
 ts.\n\nBiography: Mahmut Selman Sakar is a Tenure Track Assistant Professo
 r in the Institutes of Mechanical Engineering and Bioengineering at EPFL\,
  and the head of the MicroBioRobotic Systems (MICROBS) Laboratory. He obta
 ined his PhD in Electrical and Systems Engineering from the University of 
 Pennsylvania. He has done pioneering work on the development of tissue-eng
 ineered biological machines while working as a postdoctoral associate at t
 he Massachusetts Institute of Technology. He was a research scientist at E
 TH Zurich\, exploring advanced manufacturing and magnetic manipulation tec
 hniques at microscale\, before joining EPFL in 2016. His current work focu
 ses on the applications of microrobotics technology in life and health sci
 ences including mechanobiology\, neuroscience\, and minimally invasive med
 icine. He is a recipient of ERC Starting (2017) and Proof of Concept Grant
 s (2021).
LOCATION:MED 0 1418 https://plan.epfl.ch/?room==MED%200%201418 https://epf
 l.zoom.us/j/65387864766
STATUS:CONFIRMED
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