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SUMMARY:Mechanism and functions of nascent chromatin assembly during DNA r
 eplication
DTSTART:20221213T161500
DTEND:20221213T180000
DTSTAMP:20260921T204400Z
UID:88dd33637d3848bc40b63490b8f7529bcd8c58f483b0e5aff209ceaa
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Francesca Mattiroli (Hubrecht Institute)\nAt every cell 
 cycle\, chromatin must be accurately replicated to control development and
  tissue homeostasis. Chromatin is replicated simultaneously with DNA in S 
 phase of the cell cycle. A key regulator of this process is Chromatin Asse
 mbly Factor-1 (CAF-1). How CAF-1 performs its function at replication fork
 s and how this crosstalks to DNA replication and cell cycle progression re
 mains unclear. Here\, we use biochemical reconstitutions\, genomics and ce
 ll biology to investigate the mechanism of CAF-1 in S phase of the cell cy
 cle\, and the consequences for epigenome stability and cell survival.\n 
LOCATION:CH G1 495 https://plan.epfl.ch/?room==CH%20G1%20495
STATUS:CONFIRMED
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