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SUMMARY:Illuminating the regulation of gene expression at the single‐mol
 ecule level
DTSTART:20221214T111500
DTEND:20221214T123000
DTSTAMP:20260307T125656Z
UID:3ce89f2c9bca3cdf72b245904c9e2d49335b3d2baf049d23e1676a99
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Sebastian Deindl (Uppsala University)\nMany vital proces
 ses are regulated by the packaging of eukaryotic genomes into nucleosomes 
 and chromatin. The regulation of chromatin requires the precisely orchestr
 ated interplay of  various chromatin-associated proteins. These include 
  sequence-specific binding factors as well as ATP-dependent chromatin remo
 deling enzymes (remodelers)\, which use their ATPase motor to alter the di
 stribution and composition of nucleosomes. In order to understand the mech
 anisms of these chromatin-associated factors\, a quantitative characteriza
 tion of their complex real-time dynamics is needed. We developed novel flu
 orescence-based imaging methods that facilitate the study of these process
 es at the single-molecule level. In this talk\, I will describe the new me
 thodology and its applications. 
LOCATION:CH G1 495 https://plan.epfl.ch/?room==CH%20G1%20495
STATUS:CONFIRMED
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