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SUMMARY:Neuro-X Seminar: A whole-brain approach to investigating mouse beh
 avior using functional ultrasound imaging
DTSTART:20230227T130000
DTEND:20230227T140000
DTSTAMP:20260916T044057Z
UID:44c5c0a88b72e28a3216b1995433c253605fd813f73246be6f064134
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Bradley Edelman\nTraditional approaches to addressing syste
 ms neuroscience questions involve studying the role of individual brain re
 gions in animal behavior. However\, behavior is influenced by widely distr
 ibuted brain networks and therefore benefits from large scale neural recor
 dings. Functional ultrasound (fUS) is a novel imaging technique that enabl
 es brain-wide recordings in behaving mice and can address this need. In th
 is talk I will first present recent efforts aimed at advancing the integra
 tion of fUS into the systems neuroscience toolbox. This work includes the 
 development of a novel cranial window implant that allows for chronic whol
 e-brain fUS recordings as well as the combination of fUS with optogenetic 
 manipulations in awake head-fixed mice. I will then discuss how pairing th
 ese advancements in fUS technology with a recently developed facial expres
 sion classification method allows us to describe the neural correlates of 
 behavior states in mice at the whole-brain level.\n 
LOCATION:BM 5202 https://plan.epfl.ch//?room==BM%205202 https://epfl.zoom.
 us/j/68814034506?pwd=R3ZkaE9SVStna3U5aTA1QXB4cjgyQT09
STATUS:CONFIRMED
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