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SUMMARY:The Adventurous Journey from Hematopoietic to Leukemic Stem Cells
DTSTART:20230302T140000
DTEND:20230302T150000
DTSTAMP:20260506T123904Z
UID:d4c47c5b782082a0af36c354dbf207577e456cba70e67a6c14732e35
CATEGORIES:Conferences - Seminars
DESCRIPTION:Pr. Dr. Andreas Trumpp | Heidelberg | Germany\n\n	Stem cells a
 re essential for maintaining regenerative tissues and are critical compone
 nts of repair in response to tissue injury and infection.\n	 \n	Moreover\
 , genetic alterations of stem cells and their progeny can lead to the gene
 ration of “cancer stem cells” that drive tumorigenesis\, therapy resi
 stance and metastasis in hierarchically organized cancer entities.\n	 \n	
 Our group explores the principles of normal and diseased stem cell functi
 on as well mechanisms of therapy resistance at the molecular\, genomic an
 d single cell level.\n	 \n	We also use liquid biopsies in combination wit
 h single cell analysis and organoids to analyze breast cancer patients in
  a longitudinal manner to identify and overcome resistance mechanisms wit
 hin a personalized and precision oncology program.\n	 \n	Advanced mouse P
 DX models in combination with patient samples and multidimensional analyt
 ical and functional technologies are used to fill the research pipeline fr
 om mechanistic understanding to translation into innovative strategies wi
 th the aim to target therapy-resistant AML and pancreatic cancer cells in 
 clinical settings.\n
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/66051101511
STATUS:CONFIRMED
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