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SUMMARY:Neuro-X Seminar: Movement planning as a window into hierarchical m
 otor control
DTSTART:20230615T130000
DTEND:20230615T140000
DTSTAMP:20260511T050406Z
UID:80293865eb69c0eba11226f9b71f2fc5811d5a87f4cd1f35e07d6845
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof Katja Kornysheva\nAbstract: The ability to organise one's
  body for action without having to think about it is taken for granted\, w
 hether it is handwriting\, typing on a smartphone or computer keyboard\, t
 ying a shoelace or playing the piano. When compromised\, e.g. in stroke\, 
 neurodegenerative and developmental disorders\, the individuals’ study\,
  work and day-to-day living are impacted with high societal costs. Until r
 ecently\, indirect methods such as invasive recordings in animal models\, 
 computer simulations\, and behavioural markers during sequence execution h
 ave been used to study covert motor sequence planning in humans. In this t
 alk\, I will demonstrate how multivariate pattern analyses of non-invasive
  neurophysiological recordings (MEG/EEG)\, fMRI\, and muscular recordings\
 , combined with a new behavioural paradigm\, can help us investigate the s
 tructure and dynamics of motor sequence control before and after movement 
 execution. Across paradigms\, participants learned to retrieve and produce
  sequences of finger presses from long-term memory. Our findings suggest t
 hat sequence planning involves parallel pre-ordering of serial elements of
  the upcoming sequence\, rather than a preparation of a serial trajectory 
 of activation states. Additionally\, we observed that the human neocortex 
 automatically reorganizes the order and timing of well-trained movement se
 quences retrieved from memory into lower and higher-level representations 
 on a trial-by-trial basis. This echoes behavioural transfer across task co
 ntexts and flexibility in the final hundreds of milliseconds before moveme
 nt execution. These findings strongly support a hierarchical and dynamic m
 odel of skilled sequence control across the peri-movement phase\, which ma
 y have implications for clinical interventions.\n\nShort CV:\n\nDr Katja K
 ornysheva is an Assistant Professor and Co-Director of the Centre for Huma
 n Brain (CHBH) at the University of Birmingham\, UK. Dr Kornysheva studies
  the physiological and informational processes underlying action planning 
 and execution\, sequencing and timing\, as well as disorders of the latter
  using a combination of non-invasive brain\, muscular and behavioural reco
 rdings (fMRI\, MEG/EEG\, EMG\, dynamics\, kinematics\, motor timing). Afte
 r a PhD in Psychology (2011\; Dr. rer. nat.\, summa cum laude) undertaken 
 at the Max Planck Institutes in Leipzig and Cologne\, Katja commenced her 
 Marie Curie Postdoctoral Fellowship at the UCL Institute of Cognitive Neur
 oscience in London. She was subsequently awarded the prestigious Sir Henry
  Wellcome Postdoctoral Fellowship in 2012 to study motor learning and timi
 ng in humans at UCL and rodent models in collaboration with the Neuroscien
 ce Department at the Erasmus Medical Centre Rotterdam. In July 2017\, Katj
 a joined the School of Psychology and Neuroimaging Unit at Bangor Universi
 ty as a Lecturer and subsequently transferred to the CHBH and the School o
 f Psychology at the University of Birmingham in December 2021. Katja recei
 ved the Academy of Medical Sciences Springboard Award in 2021 to study the
  neural basis of sequence planning in individuals with developmental coord
 ination disorder (DCD)/dyspraxia and started her Co-Directorship of the CH
 BH in 2022.\n 
LOCATION:H8-1-D https://plan.epfl.ch//?room==H8%201%20144.167 https://epfl
 .zoom.us/j/67687138339?pwd=S2ZDRHhicHFBT0VXa1hsb0VQWmhiUT09
STATUS:CONFIRMED
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