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SUMMARY:Honorary Lecture Viesturs Simanis - Cold fission: how to split a c
 ell at room temperature
DTSTART:20230928T171500
DTEND:20230928T190000
DTSTAMP:20260930T194659Z
UID:d9ebe90e143f0db7bba75f129ec3fe0e9b12d0831e6495e6c2967c5c
CATEGORIES:Inaugural lectures - Honorary Lecture
DESCRIPTION:Prof. Viesturs Simanis  Bio: \nI was born in London\, UK. I di
 d my BA Degree in Biochemistry at Imperial College\, London\, passing with
  First class honours\, and was awarded the Governor’s Prize. I did my Ph
 D with Prof David Lane at Imperial College\, studying cellular sequences t
 hat bind T antigen in SV40-transformed cells. My postdoctoral studies were
  with Prof. Paul Nurse (ICRF\, London)\, working on cell cycle control\, u
 sing the fission yeast Schizosaccharomyces pombe as a model. I was appoint
 ed chercheur associé at ISREC in 1989\, and then Associate Professor at E
 PFL in 2006. My lab studies cell cycle control\, with a focus on how the c
 ell cycle is coordinated during mitotic division and meiosis.\nProgram\n17
 :15 - 17:25 Introduction by Andy Oates and Joachim Lingner\n17:25 - 18:25 
 Lecture by Viesturs Simanis\n18:30  Apéritif / SV Hall\n\nThe Lecture w
 ill be retransmitted to Campus Biotech room B1-02-B.\n\nAbstract\nTo repro
 duce itself\, a cell must first duplicate its genome (S-phase)\, then part
 ition it to ensure that each daughter cell receives a complete copy (mitos
 is)\, and finally\, divide itself to generate two daughter cells (cytokine
 sis). To maintain the integrity of its genome\, a cell must execute DNA sy
 nthesis\, mitosis\, and cytokinesis once per cycle\, in the correct order\
 , with high fidelity. The ground rules of cell cycle control were establis
 hed through the study of model organisms and analysis of extracts prepared
  from dividing cells. These identified cellular components that are import
 ant for the cell cycle or its regulation. I shall discuss our studies of t
 he S. pombe Septation Initiation Network (SIN)\, which is important for ce
 ll division. Failure of SIN signalling blocks cytokinesis\, while unschedu
 led SIN signalling uncouples cytokinesis from the rest of the cell cycle.\
 n\n\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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