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SUMMARY:IEM Seminar Series: Labs and Organs on Chip for Health and Climate
DTSTART:20230712T140000
DTEND:20230712T150000
DTSTAMP:20260427T204141Z
UID:fa0e4e68d6e07974132ea19bb4d0b28d310b3e273db1a6c4f44ac59a
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Albert van den Berg\,\nBIOS/Lab on a Chip group\, MESA+ 
 Institute\nUniversity of Twente\, The Netherlands\nAbstract\nThe recent ra
 pid developments in bionanotech and micro/nanofluidic technologies has ena
 bled the realization of miniaturized laboratories. These Labs-on-a-Chip wi
 ll play an important role in future medicine\, both in point-of-care devic
 es for drug or biomarker monitoring\, as well as in early diagnostic devic
 es. Microfluidics can also be exploited to manipulate and experiment with 
 cells on chip. We have developed a microsystem for sperm analysis and sele
 ction for artificial insemination\, where we can electrically detect and s
 ort healthy sperm cells. Apart from diagnostic and cell manipulation devic
 es\, microfluidic devices are increasingly used to realise advanced diseas
 e and organ-models\, as illustrated by the blood-brain barrier chip\, a bl
 ood vessel on a chip to study atherosclerosis and cancer spheroids on chip
  for dynamic drug dosing. These Organs on Chip may lead to more rapid and 
 cheaper drug development\, personalised medicine and improved disease mode
 ls\, while minimizing or even eliminating animal testing (3R principle). W
 e have developed a Translational Organ on Chip Platform (TOP) that enables
  simple plug and play connection of different Organ on Chip modules to a f
 luidic base plate. Finally\, a microfluidic impedance spectroscopy system 
 that can monitor the calcification of coccolithophores (algae)\, which pla
 ys an important role in the oceanic carbon cycle\, and some preliminary re
 sults on the study of accelerated weathering of olivine using micoreactors
  will be presented.\n \nBiography\nProfessor Albert van den Berg received
  his MSc in applied physics in 1983\, and his PhD in 1988 both at the Univ
 ersity of Twente\, the Netherlands. From 1988-1993 he worked in Neuchatel\
 , Switzerland\, at the CSEM and the University of Neuchatel (IMT) on minia
 turized chemical sensors. In 2000 he was appointed as full professor on Mi
 niaturized Systems for (Bio)Chemical Analysis in the faculty of Electrical
  Engineering and part of the MESA+ Institute for Nanotechnology. In 1994 h
 e initiated together with Prof. Bergveld the international MicroTAS confer
 ence series. He published over 500 peer reviewed publications (H=69 WoS\, 
 H=94 Google Scholar) a.o. in Science\, Nature\, PNAS\, PRL\, Angewandte\, 
 NanoLetters\, ACS Nano etc\, and from his group > 10 spin-off companies st
 arted. He received several honors and awards such two ERC Advanced (2008\,
  2015) and four ERC Proof of Concept (2011\, 2013\, 2016\, 2020) grants\, 
 Simon Stevin award (engineering sciences\, 2002)\, Spinoza prize (2009)\, 
 Distinguished University Professor (Twente\, 2010)\, Distinguished Profess
 or (South China Normal University SNCU (China)\, 2012)\, Consulting Profes
 sor at Northwestern Polytechnic University NPU (China)\, 2017) and member 
 of the Royal Dutch Academy of Sciences (KNAW) (board member from 2011-2016
 ). From 2014-2018 he was scientific director of the MIRA institute for Bio
 medical Engineering. In 2017 he became co-PI of the Max Planck - Universit
 y of Twente Center for Complex Fluid Dynamics. In 2018 he became (co)direc
 tor of MESA+ institute for Nanotechnology. He has been editor of Sensors a
 nd Actuators B\, cofounding member of the editorial board of the RSC journ
 al Lab on a Chip\, founding member of EUROoCS\, the European Organ on Chip
  Society and founding director of the CBMS\, the Chemical and Biological M
 icrosystems Society. In 2022 he was elected member of the SATW (CH). His c
 urrent research interests are micro/nanofluidics\, Labs on Chip and sensin
 g for health and sustainability and Organs on Chip. His current activities
  include acting as one of the quartermasters of the UT Climate Centre.\n 
LOCATION:ELA 1 https://plan.epfl.ch/?room==ELA%201
STATUS:CONFIRMED
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