BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Memento EPFL//
BEGIN:VEVENT
SUMMARY:Microsecond Time-Resolved Cryo-EM and Water in No Man's Land
DTSTART:20230905T100000
DTSTAMP:20260510T045103Z
UID:21385abc6bfc80fcbe0a1dcfa4b505ab286f17f6318442c4967f6c8b
CATEGORIES:Conferences - Seminars
DESCRIPTION:Ulrich Lorenz\n\n\n\n\n\n\n\n\nProf. Ulrich Lorenz\nLaboratory
  of Molecular Nanodynamics (LND)\n \nProteins provide the machinery of li
 fe\; however\, our understanding of their function has remained fundamenta
 lly incomplete\, as observing them in action has largely remained elusive.
  Recently\, my group has introduced microsecond time-resolved cryo-EM\, a 
 novel technique enabling such observations\, with near-atomic spatial and 
 microsecond temporal resolution. I will discuss the features our method an
 d present observations of the motions of the capsid of CCMV\, a plant viru
 s\, which illustrate the potential of our technique to fundamentally advan
 ce our understanding of proteins. Additionally\, I will discuss our closel
 y related research on water in so-called “no man's land”\, a temperatu
 re range in the deeply supercooled regime that cryo samples have to traver
 se safely during vitrification. We have probed the complete structural evo
 lution of water during this process\, a feat that researchers had pursued 
 unsuccessfully for over 40 years and that sheds new light on the origin of
  the water anomalies.\n\n\n\n\n\n\n\n
LOCATION:BCH 2201 https://plan.epfl.ch/?room==BCH%202201
STATUS:CONFIRMED
END:VEVENT
END:VCALENDAR