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SUMMARY:EPFL BioE Talks SERIES  "Generative Modelling to Understand Health
  and Disease Across Cells\, Tissues and Perturbations"
DTSTART:20231113T160000
DTEND:20231113T170000
DTSTAMP:20260406T121627Z
UID:dc1667e4cd6f74726f8a5cb074b0c65d9e70151f7119a07eac4c90ad
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Mohammad Lotfollahi\, Wellcome Sanger Institute\, Cambri
 dge (UK)\nWEEKLY EPFL BIOE TALKS SERIES\n\nAbstract:\nThe advancements in 
 single-cell technologies have enabled the generation of datasets comprisin
 g information from millions of cells. These datasets called 'atlases\,' in
 clude data from different conditions and individuals across multiple modal
 ities\, offering insights into cellular processes and states in various sc
 enarios. I will demonstrate generative approaches to model cellular hetero
 geneity and how cells interact in tissues and respond to perturbations. Fi
 nally\, I will discuss how linking patient metadata and single-cell genomi
 cs can enable the construction of population-level atlases across thousand
 s of samples and the challenges in such scenarios when dissecting noise fr
 om biologically meaningful signals.\n\nBio:\nI have recently completed my 
 PhD in Computational Biology at the Technical University of Munich (TUM) a
 nd Helmholtz Munich under the supervision of Fabian Theis. I am also a mem
 ber of ELLIS. I am the director of machine learning research at Relation T
 herapeutics and also a scientist at Helmholtz Munich and also incoming fac
 ulty at Wellcome Sanger Institute.\n\nMy research focuses on developing AI
 /ML algorithms for biomedical data\, with a specific emphasis on single-ce
 ll technologies for diagnostics\, therapeutics\, and drug discovery. I hav
 e received multiple awards for my research (see example) and have been fea
 tured in press/journals (see research). Additionally\, I have been awarded
  multiple fellowships\, grants\, and scholarships\, including those from J
 oachim Hertz\, EMBL\, and Meta.\n\nI have been offered a faculty position 
 directly after my PhD (rare in Biology) at the Wellcome Sanger Institute\,
  a leading program contributing to the Human Cell Atlas project. As part o
 f this role\, I will be hiring PhD students from the University of Cambrid
 ge.\n\nIn addition to my academic activities\, I have industry experience 
 as a researcher\, consultant\, and advisor in both biotechnology and ML/AI
  companies\, including:\n\n    Cellarity\n    Meta AI\n    SANTA 
 ANA Bio\n    Relation Therapeutics\n\n\n\n\nZoom link (with one-time re
 gistration for the whole series) for attending remotely: https://go.epfl.c
 h/EPFLBioETalks\n\n\nInstructions for 1st-year Ph.D. students who are unde
 r EDBB’s mandatory seminar attendance rule:\nIF you are not attending in
 -person in the room\, please make sure to\n\n	send D. Reinhard a note befo
 re noon on seminar day\, informing that you plan to attend the talk online
 \, and\n	be signed in on Zoom with a recognizable user name (not a pseudon
 ym making it difficult or impossible to be identified).\n\nStudents attend
 ing the seminar in-person should collect a confirmation signature after th
 e talk - please print your own signature sheet beforehand (71 kB pdf avail
 able for download here).
LOCATION:BM 5202 https://plan.epfl.ch/?room==BM%205202 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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