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SUMMARY:EPFL BioE Talks SERIES  "Targeting TCR and Co-receptor Signaling i
 n T Cell-Mediated Immunity"
DTSTART:20231120T160000
DTEND:20231120T170000
DTSTAMP:20260504T153446Z
UID:14a3318c5e9a76cc279b1b4d878ae9a5178691a42eeefc66fe8996c6
CATEGORIES:Conferences - Seminars
DESCRIPTION:Ricardo A. Fernandes\, Ph.D.\, Group Leader\, CAMS Oxford Inst
 itute\, Nuffield Department of Medicine\, University of Oxford (UK)\nWEEKL
 Y EPFL BIOE TALKS SERIES\n\nAbstract:\nThe potency of the T cell response 
 against pathogens or cancer cells is determined by the signalling output f
 rom two distinct classes of immune receptors: the T cell receptor and co-r
 eceptors\, which include activating and inhibitory checkpoint receptors su
 ch as CD28 or PD-1 and CTLA-4\, respectively. Here\, we will provide an up
 date on our latest work in targeting T cell receptors and inhibitory recep
 tors to modulate T cell responses.\n\nBio:\nDr. Ricardo Fernandes is a Gro
 up Leader at the CAMS Oxford Institute/NDM and Nuffield Department of Medi
 cine at the University of Oxford. He obtained his PhD at Oxford\, working 
 with Simon Davis on the mechanism of TCR triggering. Later moved to Stanfo
 rd\, where he developed novel bispecific proteins that take advantage of e
 ndogenous membrane phosphatases to shut down signalling by surface recepto
 rs. The Fernandes' Lab applies protein engineering to decipher functional 
 and structural correlates of immune receptor signalling and identify new t
 herapeutic approaches to modulate T cell function in autoimmune and cancer
  settings.\n\n\nZoom link (with one-time registration for the whole series
 ) for attending remotely: https://go.epfl.ch/EPFLBioETalks\n\n\nInstructio
 ns for 1st-year Ph.D. students who are under EDBB’s mandatory seminar at
 tendance rule:\nIF you are not attending in-person in the room\, please ma
 ke sure to\n\n	send D. Reinhard a note before noon on seminar day\, inform
 ing that you plan to attend the talk online\, and\n	be signed in on Zoom w
 ith a recognizable user name (not a pseudonym making it difficult or impos
 sible to be identified).\n\nStudents attending the seminar in-person shoul
 d collect a confirmation signature after the talk - please print your own 
 signature sheet beforehand (71 kB pdf available for download here).
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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