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SUMMARY:Advancing Computational Medicine With Whole-Body Metabolic Modelli
 ng
DTSTART:20240125T103000
DTSTAMP:20260501T055452Z
UID:ed7b3b8e053bbcf087fedc88c98b4523a16cf4f0577b26813d3818c9
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Ines Thiele\, National University of Ireland\, Galway (I
 RE)\ndouble feature BIOENGINEERING SEMINAR\n\n(see details of preceding ta
 lk HERE)\n\nAbstract:\nHuman metabolism is a complex interplay of biochemi
 cal transformations occurring in the different organs in the human body. M
 oreover\, whole-body metabolism is modulated by genetic and environmental 
 factors as well as by the microbes that live in and around us. To untangle
  these complex relationships\, computational modelling approaches are requ
 ired. To this end\, we have developed the first sex-specific\, organ-resol
 ved models of human metabolism. Here\, I will present these whole-body mod
 els and demonstrate how they can be used to investigate whole-body metabol
 ic changes associated with 1. genetic disorders\, 2. different gut microbi
 al compositions associated with health and disease\, and 3. for personalis
 ed medicine. These examples will highlight how these models can be used to
  systematically investigate metabolic changes in health and disease.\n\nBi
 o:\nProf. Ines Thiele earned her PhD in bioinformatics from the University
  of California\, San Diego\, in 2009. From 2009 until 2013\, Ines Thiele w
 as an Assistant Professor at the University of Iceland. From April 2013 un
 til January 2019\, she was an Associate Professor at the University of Lux
 embourg. Since February 2019\, Ines Thiele is a Professor for Systems Biom
 edicine at the National University of Ireland\, Galway. In 2013\, Ines Thi
 ele received the ATTRACT fellowship from the Fonds National de la Recherch
 e (Luxembourg). In 2015\, she was elected as EMBO Young Investigator. In 2
 017\, she was awarded the prestigious ERC starting grant. She is an author
  of over 80 international scientific papers and reviewer for multiple jour
 nals and funding agencies.\n\n\n\n\nZoom link for attending remotely: http
 s://epfl.zoom.us/j/69495424813\n\n\nNOTE: food & drinks will be served aft
 er seminar\, to encourage networking.
LOCATION:CH G1 495 https://plan.epfl.ch/?room==CH%20G1%20495 https://epfl.
 zoom.us/j/69495424813
STATUS:CONFIRMED
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