BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:The Michael J. Fox Foundation - Therapeutics Pipeline Program DTSTART;VALUE=DATE:20240627 DTSTAMP:20260510T215943Z UID:5f7d37dbec63b6fdbed670a249562615e81ded3cef5eb10bdf89afa1 CATEGORIES:Call for proposal DESCRIPTION:The Parkinson’s Disease Therapeutics Pipeline Program advanc es therapeutic development through pre-clinical and/or into clinical testi ng of approaches addressing unmet needs of people with PD with clear poten tial to prevent\, stop\, or delay disease progression or to reduce the bur den of daily symptoms. As the requirements for delivering new treatments i nto the market depend on specialized expertise and resources\, a unique go al of this program is to promote clearer paths to commercialization and ma rket access by the PD community. Therefore\, we are only accepting applica tions from industry groups or academic teams working in collaboration with a dedicated industry partner capable of further commercial development of a promising intervention.\n\nMJFF prioritizes pre-clinical and clinical p rograms that may slow\, stop\, or prevent disease progression\, efforts th at address moderate-to-advanced motor or non-motor symptoms of Parkinson ’s not well-managed by current treatments such as advanced gait disturba nces (e.g.\, balance issues linked to falls\, freezing) and cognitive chan ges.\n\nFor this program\, MJFF will not consider proposals focused on the following:\n\n Applications seeking to identify new intervention targets (e.g.\, large-scale screening or genomic/transcriptomic analyses).\n Appli cations seeking to validate a target with only tool compounds or biologica l manipulations that have no viable path for further drug optimization and development.\n Applications seeking to test reformulation of commercially available drugs via a new route of administration.\n Application seeking to assess efficacy of dietary supplements.\n\n\nFunding:\nfrom $250\,000 f or smaller\, targeted programs to upwards of $2M for larger\, multi-stage preclinical and/or clinical programs\n\nDuration:\n1 to 2 years for pre-cl inical programs\n2 to 3 years for clinical programs\n\nEligibility:\nAppli cations may be submitted by researchers or clinicians in:\n \n\n U.S. and non-U.S. public and private non-profit entities\, such as universities\, colleges\, hospitals\, laboratories\, units of state and local governments \, and eligible agencies of the federal government in collaboration with b iotechnology/pharmaceutical/medical device companies\, or other publicly o r privately held for-profit entities.\n MJFF encourages the inclusion of r esearchers who span career stages.\n Early career investigators (within 1- 7 years of first independent appointment or equivalent) are encouraged to apply and are permitted to serve as Principal Investigator (PI)\; Post-doc toral fellows are permitted to serve as Co-Principal Investigator (Co-PI). Training and fellowship activities are not supported through this program .\n\n\nHow to Apply: The two-stage application process begins with an LOI\ , which can be submitted on a rolling basis on the MJFF Grant Portal. Inst ructions for pre-proposal submission vary if submitting a pre-clinical pro ject or a clinical project. Selected applicants will be notified within th ree weeks and will be invited to submit a full proposal by one of the four deadlines (see below). Budgets should be formulated to include 15% OH.\n\ nDeadlines (full proposals):         11 January 2024\n                                                             14 March 2024\n                                                             16 May 2024\n                                                            27 June 2024\n\nFurther information:\n\n\n More information about the program is available here and the full RFA is available here\n Application portal can be found here\n\nFor any other questions\, please contact the Researc h Office LOCATION: STATUS:CONFIRMED END:VEVENT END:VCALENDAR