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SUMMARY:EESS talk - Student presentation on "Imprints of the urban environ
 mental exposome on georeferenced brain images\, affective functions\, and 
 cognition"
DTSTART:20240305T121500
DTEND:20240305T124500
DTSTAMP:20260501T090531Z
UID:752d96ca878b30faae39d33b3750cf60b00667e56f39213ef6b93a90
CATEGORIES:Conferences - Seminars
DESCRIPTION:Marco Vieira Ruas\, LGB\nAbstract:\nIn the context of increasi
 ng lifespans\, prevalent age-related brain disorders\, and widespread urba
 nisa9on\, understanding the relationship between the urban environmental e
 xposomeand brain health is imperative. Beyond the beneficial effects of ci
 ty living on infant survivaland upbringing\, emerging evidence suggests it
 s potential adverse effects on the brain. Given the significant burden of 
 cognitive decline\, associated depression\, and other aging-related\nbrain
  disorders on global disability\, investigating the influence of modifiabl
 e life factors on brain health becomes crucial. In our study\, we analysed
  data stemming from the longitudinal CoLaus|PsyCoLaus cohort. We examined 
 anxiety using the State Trait Anxiety Inventory (STAI) and well-being with
  the Global Assessment of Functioning (GAF). We tested individuals’ glob
 al cognitive performance with the Mini Mental State Examination (MMSE). Fr
 om the nested BrainLaus project\, we acquired brain data via magnetic reso
 nance imaging (MRI)\, including regional brain volumes (ROI) and White MaT
 er (WM) tracts\, assessed in relation to myelin content\, axonal density\,
  free water\, and volume.We evaluated the urban environmental exposome aro
 und the participants’ home addresses using georeferenced data considerin
 g factors like vegetation (ARVI\, NDVI)\, air pollution (NO2\,PM10)\, nigh
 t-time traffic noise\, daylight radiation intensity and duration\, public 
 transport accessibility and Land Surface Temperature (LST). Our results in
 dicate a spatial dependency for mood disorders and cognition in the city o
 f Lausanne. Further\, we observed significant associations between exposom
 e variables\, particularly vegetation\, air pollution and LST\, and mood d
 isorders. Addi9onally\, we identified spatial associations between ROI and
  mood/cognition. Employing a spatial interaction model\, we determined spe
 cific thresholds of the environmental exposome\, affecting the association
  between ROI and mood/cognition. Finally\, we found a significant positive
  correlation between the free water content in specific brain WM tracts an
 d LST. Our research underscores the impact of urban living on brain health
  and highlights the challenges posed by climate warming\, offering valuabl
 e insights for futureurban planning and public health strategies.\n\nShort
  Biography:\nI was born in Aigle on 9th May 1992. I grew up in Bulle\, whe
 re I accomplished all my mandatoryeducation and high school. Before starti
 ng EPFL\, I served as a bartender and a tour guide at Maison Caillers in B
 roc for a few months\, to fund an overseas trip to New-Zealand. There\, I 
 attended English language classes\, obtained my CAE Advanced Cer9ficate\, 
 and enjoyed a memorable road trip. I studied environmental engineering at 
 EPFL\, where I obtained my\nMasters in 2020. Subsequently\, I worked for j
 ust shy of two years as a research assistant at the now-closed LASIG lab. 
 I started my PhD in March 2022 under the supervision of Dr. Stéphane Joos
 t and Pr. Bogdan Draganski\, focusing on leveraging spatial analysis techn
 ics to unravel the potential impact of geographical space and the urban ex
 posome on mood\, cognition\, and brain health. In my spare time\, I enjoy 
 climbing\, hiking\, skiing\, as well as delving into\ngeopolitics.
LOCATION:GC B1 10 https://plan.epfl.ch/?room==GC%20B1%2010 https://epfl.zo
 om.us/j/69011077410
STATUS:CONFIRMED
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