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SUMMARY:EPFL BioE Talks SERIES  "Interplay Between Lipid Membrane Mechanic
 s and Proteins’ Diffusion\, Clustering and Function"
DTSTART:20240226T121500
DTEND:20240226T131500
DTSTAMP:20260414T224437Z
UID:6722a990dc4d9c292eaed42839878696d9080d39e2a8e1def35f774e
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Patricia Bassereau\, CNRS Research Director\, Institut C
 urie\, Paris (F)\nWEEKLY EPFL BIOE TALKS SERIES (sandwiches provided)\n\nA
 bstract:\nCell membranes are highly deformable and have to be strongly cur
 ved\, for instance upon trafficking when small buds form and eventually de
 tach from cell membranes. Membrane-shaping processes always require protei
 ns\, in particular proteins with intrinsically-curved shapes or transmembr
 ane proteins with conical shapes. Moreover\, since cell membranes are flui
 d\, proteins can diffuse on/in membranes\, which allows them to redistribu
 te depending on membrane shape changes. In vitro membrane systems with con
 trolled curvature\, combined to theoretical models\, have been instrumenta
 l for understanding the rich interplay between membrane shape/tension\, pr
 otein distribution and lateral diffusion. I will summarize some results we
  have obtained with in vitro membrane systems and reconstituted trans-memb
 rane protein on membrane curvature-induced protein sorting\, on protein di
 ffusion and clustering and on the effect of membrane curvature on transpor
 t activity.\n\nBio:\nPatricia Bassereau is CNRS Directrice de Recherche at
  the Institut Curie in Paris\, France\, where she is the leader of the gro
 up "Membranes and cellular functions". She obtained a short PhD and a PhD 
 in Soft Matter at the University of Montpellier where she started her care
 er on the structure of self-assembled surfactant-based systems. She spent 
 one year as a visiting scientist at the IBM Almaden Center (San Jose\, CA\
 , USA) on thin polymer films. She moved to the Institut Curie in 1993 to w
 ork on questions related to "Physics of the cell". She develops a multidis
 ciplinary approach\, largely based on synthetic biology and biomimetic sys
 tems\, as well as quantitative mechanical and microscopy methods to unders
 tand the role of biological membranes and of their organization in cellula
 r functions such as intracellular trafficking\, endo/exocytosis or adhesio
 n. Additionally\, she studies in vitro and in cellulo the mechanics and th
 e generation of cellular protrusions. In parallel\, she contributes to a m
 ore comprehensive physical description of biomembranes by studying the con
 sequences of non-equilibrium transmembrane transport of ions on membrane m
 echanics ("active membranes")\, the relation between membrane proteins' sh
 ape and their diffusion or their lateral distribution on membranes.\n\nEdu
 cation:\nMaster: Solid State Physics (1983)\nPhD (1985)\nPhD (1990)\nHdR (
 Habilitation\, 1999)\n\nPositions:\nGDPC-Montpellier (1983-1991)\nIBM Alma
 den (USA) (1992)\nPhysical Chemistry Curie-Paris (1993-Present)\n\n\nZoom 
 link (with one-time registration for the whole series) for attending remot
 ely: https://go.epfl.ch/EPFLBioETalks\n\n\nInstructions for 1st-year Ph.D.
  students who are under EDBB’s mandatory seminar attendance rule:\nIN CA
 SE you cannot attend in-person in the room\, please make sure to\n\n	send 
 D. Reinhard a note well ahead of time (ideally before seminar day)\, infor
 ming that you plan to attend the talk online\, and\, during seminar:\n	be 
 signed in on Zoom with a recognizable user name (not any alias making it d
 ifficult or impossible to identify you).\n\nStudents attending the seminar
  in-person should collect a confirmation signature after the talk - please
  print your own signature sheet beforehand (71 kB pdf available for downlo
 ad here). IMPORTANTLY: hang on to this sheet as no signature record is bei
 ng kept by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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