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SUMMARY:Molecular Interrogation of the Surface Signaling in the Brain\; Fr
 om Light-Gated Signaling to Cancer
DTSTART:20240229T101500
DTEND:20240229T111500
DTSTAMP:20260921T081959Z
UID:8246cabd4797e7a8dd23bf864b910aba6dd6ac7626004626598fa5da
CATEGORIES:Conferences - Seminars
DESCRIPTION:Yoon Seok Kim\, Ph.D.\, Postdoctoral Scholar\, Dept of Bioengi
 neering\, Stanford University School of Medicine\, Stanford\, CA (USA)\nBI
 OENGINEERING SEMINAR\n \nAbstract:\nHow neurons translate external stimul
 i into intricate information is a pivotal question in neuroscience. My res
 earch focuses on exploring the role of cell-surface proteins in neuronal s
 ignaling. In this presentation\, I will first describe the structural and 
 molecular mechanisms of light-gated ion channels\, which are vital for the
  precise control of neuronal activity. Next\, I will present my work on un
 derstanding the unconventional K+-selectivity within light-gated signaling
  proteins\, which are promising approaches of inhibitory modulation. Third
 ly\, I will discuss my efforts in developing genetic methods to fine-tune 
 the biophysical properties of neuronal membranes through a combination of 
 chemical and molecular engineering. Finally\, I will highlight the recent 
 discovery of cell-surface pathways in pediatric brain cancer cells that ar
 e responsible for activity-driven brain cancer growth. Taken together\, th
 ese works represent advancements in our understanding of cell surface neur
 obiology\, addressing both basic and clinical aspects.\n\nBio:\nYoon recei
 ved his Bachelor's degree in neurobiology in 2013 and his M.S. in biology 
 in 2014 from Stanford University. During his Masters degree\, He studied t
 he biochemistry of postsynaptic and presynaptic membrane proteins in Thoma
 s Sudhof's lab. He then joined the Bioengineering Ph.D. program at Stanfor
 d\, co-advised by Dr. Karl Deisseroth and Dr. Brian Kobilk. After obtainin
 g his Ph.D. in Bioengineering in 2020 he became a Postdoctoral Scholar in 
 Neurology and Neurological Sciences at Stanford University's Department o
 f Bioengineering and School of Medicine.\n\n\nZoom link for attending remo
 tely\, if needed: https://epfl.zoom.us/j/65840790132
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/65840790132
STATUS:CONFIRMED
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