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SUMMARY:Dynamic Imaging Through Live Animal Clearing and Liquid-Phase TEM
DTSTART:20240301T150000
DTEND:20240301T160000
DTSTAMP:20260510T042339Z
UID:125f0d2501e2f522db312c5de2981a9fb69145bffc55175765e86fe8
CATEGORIES:Conferences - Seminars
DESCRIPTION:Zihao Ou\, Ph.D.\, Postdoctoral Research Fellow\, Wu Tsai Neur
 osciences Institute\, Dept of Materials Science & Engineering\, Stanford U
 niversity\, Stanford\, CA (USA)\nVIRTUAL BIOENGINEERING SEMINAR\n \nAbstr
 act:\nDynamic imaging is a pivotal tool for answering complex scientific q
 uestions across materials science and biology. However\, traditional optic
 al imaging platforms are hampered by limited nanoscale resolution and inad
 equate depth in biological tissues\, which restricts our understanding of 
 dynamic behaviors. This presentation will highlight two innovative imaging
  modalities that I have pioneered to extend the capabilities of high-resol
 ution dynamic imaging through breakthroughs in materials science and nanot
 echnology. First\, I will discuss the utilization of materials photonics t
 o achieve optical transparency in biological tissues. By integrating molec
 ules that significantly absorb light into a scattering medium\, we can tra
 nsform an opaque sample into a transparent window\, allowing deep investig
 ation into embedded anatomical features. Utilizing this innovation\, I hav
 e developed non-invasive imaging techniques to analyze the dynamics of neu
 ral networks in the peripheral nervous system\, without the need for compl
 ex surgery. Second\, I will present the application of liquid-phase transm
 ission electron microscopy to unravel the complex processes of nanoparticl
 e self-assembly in a fluid environment. Through dynamic imaging\, we have 
 observed a two-step crystallization kinetics of nanoparticle superlattices
  and thermally driven capillary waves at their interface with the suspensi
 on. These advancements in imaging technology hold significant promise for 
 enhancing our comprehension of materials and biological systems.\n\nBio:\n
 Zihao was trained as a materials scientist with a physicist mindset. Befor
 e joining Prof. Guosong Hong’s lab for post-doctoral research in 2020\, 
 Zihao received his Ph.D. degree from the Materials Science and Engineering
  Department at University of Illinois at Urbana-Champaign. In his Ph.D. re
 search with Prof. Qian Chen\, he focused on studying the dynamic self-asse
 mbly behaviors of nanoparticles using liquid-phase transmission electron m
 icroscopy and revealed a two-step nonclassical crystallization pathway and
  capillary wave facilitated interface growth mode. Before that\, Zihao rec
 eived his B.S. degree in Physics from the School of the Gifted Young at Un
 iversity of Science and Technology of China in 2015.\n\n\nZoom link for at
 tending remotely (this is a virtual seminar): https://epfl.zoom.us/j/65356
 454106
LOCATION:https://epfl.zoom.us/j/65356454106
STATUS:CONFIRMED
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