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SUMMARY:EPFL BioE Talks SERIES  "From the Bush to the Bench: Novel Insight
 s Into the Biology of Aging From the Short-Lived African Killifish"
DTSTART:20240506T121500
DTEND:20240506T131500
DTSTAMP:20260503T115933Z
UID:f9ae8c9dd2237a6be28662fe7e2df9b25e8e0cae37f3e214c5290ced
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Alessandro Cellerino\, Scuola Normale Superiore\, Pisa (
 IT) and Leibniz Institute on Aging\, Jena (DE)\nWEEKLY EPFL BIOE TALKS SER
 IES (sandwiches provided)\n\nAbstract:\nAfrican annual fishes from the gen
 us Nothobranchius are small teleosts that inhabit temporary water bodies s
 ubject to annual desiccation due to the alternation of the monsoon seasons
 . Given their unique biology\, these fish have emerged as a model taxon in
  several biological disciplines. Their increasing popularity stems from th
 e extremely short lifespan that is the result of their specific life-histo
 ry adaptations and is retained under laboratory conditions. Nothobranchius
  furzeri\, the most popular laboratory species\, is the vertebrate species
  with the shortest lifespan recorded in captivity. Their short lifespan is
  coupled to rapid age-dependent functional decline and expression of cellu
 lar and molecular changes comparable to those observed in other vertebrate
 s\, including humans. The availability of a sequenced genome and recent de
 velopment of transgenesis makes Nothobranchius species particularly suited
  for investigating biological and molecular aspects of ageing and ageing-a
 ssociated dysfunctions. At the same time\, they also represent a unique mo
 del taxon to investigate the evolution of life-history adaptations and the
 ir genetic architecture. In this seminar I will illustrate how this model 
 system revealed novel molecular aspects related to lifespan and brain agin
 g\, particularly for what concerns mechanisms related to proteostasis.\n\n
 \nBio:\nProf. Cellerino is a world leader in aging and longevity research.
  He is an Associate Professor and Research group leader at the Scuola Norm
 ale Superiore in Pisa (IT) and the Leibniz Institute on Aging in Jena (DE)
 . Alessandro Cellerino's group focuses on studying the biology of aging us
 ing the annual fish Nothobranchius furzeri by combining comparative genomi
 cs\, transgenesis and neuroanatomy.\n\nAlessandro Cellerino trained in Bio
 logy at Scuola Normale Superiore in Pisa (M.Sc. 1991)\, where he also got 
 his Ph.D. in Neuroscience (1995). He carried out postdoctoral training in 
 Germany at the Max Planck Institute of Neurobiology in Martinsried/Munich 
 (1995) and at the University of Tübingen (1995-1997)\, before returning t
 o Pisa\, Italy\, first as researcher of the Consiglio Nazionale delle Ric
 erche (1998-1999) and then at Scuola Normale Superiore (2000-2006)\, where
  he started his own lab as Assistant in 2010 and has been Associate Profes
 sor since 2016. In 2006 Cellerino also joined the Leibniz Institute on Agi
 ng in Jena (DE)\, first as Visiting Research Scientist (2006-2007)\, then 
 as Junior Group Leader (2007-2009). Since 2020\, Alessandro Cellerino is h
 older of a prestigious Leibniz Chair at the Leibniz Institute on Aging –
  Fritz Lipmann Institute (FLI) in Jena.\n\n\nZoom link (with one-time regi
 stration for the whole series) for attending remotely: https://go.epfl.ch/
 EPFLBioETalks\n\n\nInstructions for 1st-year Ph.D. students who are under 
 EDBB’s mandatory seminar attendance rule:\nIN CASE you cannot attend in-
 person in the room\, please make sure to\n\n	send D. Reinhard a note well 
 ahead of time (ideally before seminar day)\, informing that you plan to at
 tend the talk online\, and\, during seminar:\n	be signed in on Zoom with a
  recognizable user name (not any alias making it difficult or impossible t
 o identify you).\n\nStudents attending the seminar in-person should collec
 t a confirmation signature after the talk - please print your own signatur
 e sheet beforehand (71 kB pdf available for download here). IMPORTANTLY: h
 ang on to this sheet as no signature record is being kept by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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