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SUMMARY:EPFL BioE Talks SERIES  "Patterning\, Waves and Synchronization in
  Arrays of Cilia"
DTSTART:20240513T121500
DTEND:20240513T131500
DTSTAMP:20260406T152932Z
UID:99c898a8f42d84559fefe6f5a19e3fe9696e643844568362ef568024
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Guillermina Ramirez-San-Juan\, Living Patterns Laborator
 y\, Institute of Physics\, EPFL\, Lausanne (CH)\nWEEKLY EPFL BIOE TALKS SE
 RIES (sandwiches provided)\n\nAbstract:\nLiving organisms rely on flows to
  perform essential functions that range from swimming and feeding in unice
 llular organisms to mucus clearance in humans. These large-scale flows are
  generated by the inte­grated activity of thousands of microscopic beatin
 g filaments attached to cell surfaces (cilia). In cells\, collections of c
 ilia exhibit highly coordinated temporal patterns known as metachronal wav
 es. While patterns of cilia temporal coordination have been observed for d
 ecades\, the mechanisms underlying their formation and their contribution 
 to flow generation remain unclear. The lack of measurements of the geometr
 ic and dynamic properties of cilia arrays has limited our ability to under
 stand the mechanisms of pattern formation. In my talk I will discuss the a
 dvantages of ciliated swimmers as experimental model systems where such me
 asurements can be readily performed. Performing precise measurements and p
 erturbations of temporal patterning in cilia arrays will enable the identi
 fication of the physical mechanisms underlying the emergence of collective
  behavior. Beyond their biological significance\, arrays of cilia provide 
 an accessible experimental platform to explore the physics of multi-scale 
 pattern formation.\n\n\nBio:\nGuillermina Ramirez-San-Juan earned her PhD 
 in Biophysics under the supervision of Margaret Gardel at the University o
 f Chicago. Her work in the Gardel lab focused on understanding how cell mi
 gration is guided by the geometry of the extra-cellular environment. Addit
 ionally\, during her doctoral studies she collaborated closely with the Ho
 rne-Badovinac lab to investigate the role of cytoskeletal patterning in or
 gan morphogenesis.\nThe experience of collaborating across different field
 s inspired her to become a joint postdoctoral researcher with Wallace Mars
 hall at the University of California\, San Francisco and Manu Prakash at S
 tanford University. There she became interested in combining tools from ce
 ll biology and fluid mechanics to study flow generation by ciliary arrays.
 \nSince 2023 she is Tenure-Track Assistant Professor at EPFL in the Insti
 tute of Physics (School of Basic Sciences)\, where she is heading the Livi
 ng Patterns Laboratory.\nGuillermina Ramirez-San-Juan has always been fasc
 inated by the diversity of patterns observed in biological systems\, wheth
 er they exist at the subcellular\, cellular\, tissue or organism scales.\n
 When not in the lab she is in the kitchen experimenting with new protocols
  a.k.a. recipes or running by the nearest lake.\n\n\nZoom link (with one-t
 ime registration for the whole series) for attending remotely: https://go.
 epfl.ch/EPFLBioETalks\n\n\nInstructions for 1st-year Ph.D. students who ar
 e under EDBB’s mandatory seminar attendance rule:\nIN CASE you cannot at
 tend in-person in the room\, please make sure to\n\n	send D. Reinhard a no
 te well ahead of time (ideally before seminar day)\, informing that you pl
 an to attend the talk online\, and\, during seminar:\n	be signed in on Zoo
 m with a recognizable user name (not any alias making it difficult or impo
 ssible to identify you).\n\nStudents attending the seminar in-person shoul
 d collect a confirmation signature after the talk - please print your own 
 signature sheet beforehand (71 kB pdf available for download here). IMPORT
 ANTLY: hang on to this sheet as no signature record is being kept by anyon
 e else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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