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SUMMARY:IMX Seminar Series - Short Peptides and Amino Acids as Building Bl
 ocks for Sustainable Materials and Coatings
DTSTART:20241209T131500
DTEND:20241209T141500
DTSTAMP:20260921T170106Z
UID:80e0dc3f7acc2eb309baf83984f366d203752613951cdc79c3d233b9
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Meital Reches\, Institute of Chemistry and the Center fo
 r Nanoscience and Nanotechnology\, the Hebrew University of Jerusalem\nSho
 rt peptides and amino acids are promising building blocks for sustainable 
 materials as they are non-toxic and biodegradable. In this lecture\, I wil
 l present bio-inspired functional coatings that are spontaneously formed b
 y extremely short peptides and commercially available amino acids. These c
 oatings self-assemble on metals\, oxides\, and polymers under mild conditi
 ons without any need for a curing step and can serve many functions includ
 ing self-cleaning and antifouling.1 We specifically showed that extremely
  short peptides can self-assemble into a coating that prevents the first s
 tep of biofouling\, which involves the adsorption of bioorganic molecules 
 to the substrate.2 The coating significantly reduces the attachment of va
 rious organisms\, such as bacteria\, viruses and fungi\, to surfaces.3\, 4
  Another function that these peptide-based coatings can mediate is the ad
 hesion of mammalian cells to implants. This function is important for the 
 integration of implants into the human body. Moreover\, these peptides sel
 f-assemble in solution into particles that adsorb and release active compo
 unds that synergistically reduce the number of bacteria\, viruses and fung
 i.5 They can also be integrated into polymeric films by a simple co-extru
 sion protocol to form active polymeric films.6 Finally\, we showed that a
 n individual amino acid can self-assemble into a superhydrophobic coating 
 that can provide surfaces with the ability to self-clean.7\nReferences\n(1
 ) Maity\, S.\; Nir\, S.\; Zada\, T.\; Reches\, M. Self-assembly of a tripe
 ptide into a functional coating that resists fouling. Chemical Communicat
 ions 2014\, 50 (76)\, 11154-11157.\n(2) Duanis-Assaf\, T.\; Reches\, M.
  Factors influencing initial bacterial adhesion to antifouling surfaces st
 udied by single-cell force spectroscopy. iScience 2024\, 27 (2)\, 1088
 03.\n(3) Hu\, T.\; Agazani\, O.\; Nir\, S.\; Cohen\, M.\; Pan\, S.\; Reche
 s\, M. Antiviral Activity of Peptide-Based Assemblies. ACS Applied Materi
 als & Interfaces 2021\, 13 (41)\, 48469-48477.\n(4) Hu\, T.\; Kaganovic
 h\, M.\; Shpilt\, Z.\; Pramanik\, A.\; Agazani\, O.\; Pan\, S.\; Tshuva\, 
 E.\; Reches\, M. Ultrashort Peptides for the Self-Assembly of an Antiviral
  Coating. Advanced Materials Interfaces 2023\, 10 (6)\, 2202161. DOI:\
 n(5) Kaganovich\, M.\; Taha\, M.\; Zig\, U.\; Tshuva\, E. Y.\; Shalev\, D.
  E.\; Gamliel\, A.\; Reches\, M. Self-Assembly of a Dipeptide with a Reduc
 ed Amount of Copper into Antifungal and Antibacterial Particles. Biomacro
 molecules 2024\, 25 (2)\, 1018-1026.\n(6) Kaganovich\, M.\; Shlosman\, 
 K.\; Goldman\, E.\; Benchis\, M.\; Eitan\, T.\; Shemesh\, R.\; Gamliel\, A
 .\; Reches\, M. Fabrication of antimicrobial polymeric films by compressio
 n molding of peptide assemblies and polyethylene. Chemical Communications
  2022\, 58 (67)\, 9357-9360.\n(7) Hu\, T.\; Zhang\, Z.\; Reches\, M. A 
 self-standing superhydrophobic material formed by the self-assembly of an 
 individual amino acid. Journal of Colloid and Interface Science 2024\, 
 655\, 899-908.\n\nBio: Meital Reches is a Full Professor at the Institute 
 of Chemistry and the Center for Nanoscience and Nanotechnology\, the Hebre
 w University of Jerusalem. After completing her Ph.D. studies at Tel Aviv 
 University in 2007 and spending three years as an EMBO and an HFSP postdoc
 toral research fellow at Harvard University\, Prof. Reches established her
  independent research group at the Hebrew University in 2010.\nResearch in
  the Reches group focuses on understanding the interactions of biological 
 entities such as proteins\, bacteria\, viruses\, and cells with surfaces. 
 In addition\, her group develops peptide-based coatings to control these i
 nteractions.\nFor her innovations\, Prof. Reches was awarded with the Mari
 e Currie Alumni Association Best Innovator Award\, the Kaye Award and the 
 Tenne Family Prize in Nanoscale Sciences. \n 
LOCATION:MXF 1 https://plan.epfl.ch/?room==MXF%201
STATUS:CONFIRMED
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