BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Memento EPFL//
BEGIN:VEVENT
SUMMARY:EPFL BioE Talks SERIES  "Understanding and Controlling Mechanotran
 sduction\, From Integrins to the Nucleus"
DTSTART:20241125T121500
DTEND:20241125T131500
DTSTAMP:20260510T045157Z
UID:6f509f9e33733c7fbe7511e54d5452d38e89f7df2b6ba5e39cf3d060
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Pere Roca-Cusachs Soulere\, Institute for Bioengineering
  of Catalonia (IBEC) and Universitat de Barcelona (ES)\nWEEKLY EPFL BIOE 
 TALKS SERIES (sandwiches provided)\n\nAbstract:\nCell proliferation and di
 fferentiation\, as well as key processes in development\, tumorigenesis\, 
 and wound healing\, are strongly determined by the properties of the extra
 cellular matrix (ECM)\, including its mechanical rigidity and its composit
 ion. In this talk\, I will discuss how mechanical force is transmitted fro
 m the ECM to the nucleus\, and how this affects proteins in general\, and 
 transcription factors in particular\, by controlling their shuttling betwe
 en the cytoplasm and nucleus. Further\, I will discuss how this knowledge 
 can be used to control\, and potentially engineer\, cell mechanotransducti
 on.\n\n\nBio:\nPere Roca-Cusachs obtained his PhD in cellular biophysics i
 n 2007 from the Medical School at the University of Barcelona. He then wor
 ked in the lab of Prof. Michael Sheetz (Department of Biological Sciences\
 , Columbia University) as a post-doctoral researcher until 2011. In 2011\,
  He joined the University of Barcelona\, where he is now full professor. I
 n 2012\, he obtained a joint position as group leader at the Institute for
  Bioengineering of Catalonia (IBEC). He is an EMBO member and a recipient 
 of the EMBO Young Investigator Award\, the 2017 City of Barcelona award to
  the Life Sciences\, the 2017 Young Investigator Award of the European Bio
 physical Societies Association (EBSA)\, and an advanced grant from the ERC
 . The research of his group focuses on unraveling the physical and molecul
 ar mechanisms by which cells detect and respond to mechanical force.\n\n\n
 Zoom link (with one-time registration for the whole series) for attending 
 remotely: https://go.epfl.ch/EPFLBioETalks\n\n\nInstructions for 1st-year 
 Ph.D. students who are under EDBB’s mandatory seminar attendance rule:\n
 IN CASE you cannot attend in-person in the room\, please make sure to\n\n	
 send D. Reinhard a note well ahead of time (ideally before seminar day)\, 
 informing that you plan to attend the talk online\, and\, during seminar:\
 n	be signed in on Zoom with a recognizable user name (not any alias making
  it difficult or impossible to identify you).\n\nStudents attending the se
 minar in-person should collect a confirmation signature after the talk - p
 lease print your own signature sheet beforehand (71 kB pdf available for d
 ownload here). IMPORTANTLY: hang on to this sheet as no signature record i
 s being kept by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
END:VEVENT
END:VCALENDAR