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SUMMARY:Neuro-X seminar: Prof Julian Neumann - Deep Brain Stimulation as a
  Therapeutic Brain-Computer Interface: From Disease Signatures to AI-Drive
 n Neural Circuit Prosthetics
DTSTART:20250313T133000
DTEND:20250313T141500
DTSTAMP:20260607T133439Z
UID:76df8680ed1b47e99d0d64a0729d8171c08ac4fceccef06d6cfe98f7
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof Julian Neumann\nDeep brain stimulation (DBS) is a brain c
 ircuit intervention that can modulate distinct neural pathways for the tre
 atment of brain disorders. In recent years\, DBS has also emerged as a pow
 erful research tool\, advancing our understanding of network dysfunction i
 n neuropsychiatric diseases. Building on these insights\, advances in inva
 sive neurophysiology and MRI connectomics now offer unprecedented opportun
 ities to transform DBS into a dynamic\, patient-specific therapy—shiftin
 g from static stimulation paradigms to AI-driven\, closed-loop brain-compu
 ter interfaces (BCIs). In this lecture\, I will introduce key disease- and
  symptom-specific signatures of invasively recorded brain activity and dis
 cuss their role in the clinical pathophysiology of disorders such as Parki
 nson’s disease\, Tourette’s syndrome\, obsessive compulsive disorder\,
  and depression. I will then explore how these neural signatures originate
  within brain networks and examine the therapeutic mechanisms of invasive 
 neuromodulation across micro- and macroscopic scales. Finally\, I will pro
 vide an outlook on how machine learning-powered brain signal decoders can 
 inform closed-loop DBS algorithms to revolutionize the treatment of neurop
 sychiatric disease—enabling precise\, millisecond-scale stimulation of t
 he right network at the right time. Towards a neural circuit prosthetic t
 hat restores disrupted neural dynamics in brain disorders.
LOCATION:H8-1-D https://plan.epfl.ch/?room==H8%201%20144.167 https://epfl.
 zoom.us/j/62197745936?pwd=o0ZHlaxO2Jgh2JNbnaeZbJHX3fpYRC.1
STATUS:CONFIRMED
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