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SUMMARY:CellStudio Platform: Advancing Spatially-Resolved Analysis of Cell
  Secretion
DTSTART:20250515T101500
DTEND:20250515T113000
DTSTAMP:20260601T054012Z
UID:0d085acf6def76a7da546c1a0a53c838942bf916a3a4e8b901e12cc4
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Lourdes Basabe-Desmonts\, Microfluidics Cluster\, Resea
 rch Centre Lucio Lascaray\, University of the Basque Country UPV/EHU\, Vi
 toria-Gasteiz (ESP)\nBIOENGINEERING SEMINAR\n \nAbstract:\nIn this talk I
  will present advances in spatially-resolved cell analysis using CellStudi
 o\, a modular and accessible platform for monitoring cellular secretions. 
 Combining printing and vacuum lithography\, and bead-based biosensing\, Ce
 llStudio enables high-sensitivity detection of secreted proteins within st
 ructured cell cultures using standard lab equipment. We demonstrate its ve
 rsatility through four studies: detection of VEGF and FGF-2 in stem and ca
 ncer cells\; integration of a structure-switching aptamer for real-time VE
 GF sensing\; solid-phase presentation of growth factors via functionalized
  beads to control stimulation\; and monitoring of IFN-γ secretion from Ju
 rkat T cells under CD3/CD4 co-stimulation. Together\, these works highligh
 t CellStudio's potential as a robust\, user-friendly tool for investigatin
 g cell behaviour in controlled microenvironments.\n\nBio:\n\n\n\n\nLourdes
  Basabe studied chemistry at the Universidad Autónoma de Madrid until 200
 2. Then\, she moved to the University of Twente in The Netherlands\, where
  she completed her PhD in 2006 under the supervision of Dr. Crego Calama a
 nd Prof. David Reinhoudt at the Supramolecular Chemistry Group within the 
 MESA+ Institute for Nanotechnology. In 2006 she joined the Biomedical Diag
 nostics Institute in Dublin\, Ireland\, where in 2009 she became Team Lead
 er in Microfluidics for Platelet Biology. In 2012\, she was awarded an Ike
 rbasque Research Professorship and she moved to CICmicroGUNE in the Basque
  Country\, Spain. In 2014\, Lourdes joined the BIOMICS research group at t
 he University of the Basque Country\, led by Prof. Martinez de Pancorbo\, 
 where she established her own independent research team: BIOMICS-microflui
 dics\, focused on the development of lab-on-a-chip technologies. In June 2
 015 she co-founded the Microfluidics Cluster UPV/EHU with Dr. Fernando Ben
 ito-Lopez´s group. And in 2019 she promoted the creation of the Microflui
 dics and Biomics (M&B) Cluster UPV/EHU\, Lourdes Basabe is the director of
  the M&B Cluster UPV/EHU which is finacially supported by the Basque Gover
 nment.\nLourdes has a multidisciplinary scientific background marked by a 
 high international mobility. In 2010 Lourdes she was awarded with the UK a
 nd Ireland L'Oreal UNESCO for Women in Science Fellowship. The research of
  Lourdes Basabe-Desmonts is published in peer reviewed publications at hig
 h impact international journals (ACS Nano\, JACS\, Advanced Materials\, An
 gewandte Chemie International Edition\, Lab on a Chip\, Langmuir\, Chemica
 l Society Reviews\, etc). She is also inventor of several patents.\n\n\n\n
 \n.\n\n\nZoom link for attending remotely: https://epfl.zoom.us/j/69559099
 320\n\n\nInstructions for 1st-year Ph.D. students planning to attend this 
 talk\, who are under EDBB’s mandatory seminar attendance rule:\nIN CASE 
 you cannot attend in-person in the room\, please make sure to\n\n\n	send D
 . Reinhard a note well ahead of time (ideally before seminar day)\, inform
 ing that you plan to attend the talk online\, and\, during seminar:\n	be s
 igned in on Zoom with a recognizable user name (not any alias making it di
 fficult or impossible to identify you).\n\nStudents attending the seminar 
 in-person should collect a confirmation signature after the talk - please 
 print your own signature sheet beforehand (69 kB pdf available for downloa
 d here). IMPORTANTLY: hang on to this sheet as no signature record is bein
 g kept by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/69559099320
STATUS:CONFIRMED
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