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SUMMARY:Faculty Seminar Jacques Fellay: Genomic insights into infectious d
 iseases: from variants to clinical applications
DTSTART:20250619T121500
DTEND:20250619T131500
DTSTAMP:20260416T062006Z
UID:d8557e176ee828ed4936b3cec409f43a25def1a490009b0b2092aa93
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof Jacques Fellay\nAbstract\nAdvances in human genomics have
  improved our understanding of infectious disease susceptibility\, illumin
 ating the biological basis for individual variability in pathogen response
 . My research group has pioneered the transition from targeted genetic inv
 estigations to comprehensive multi-omic approaches in this field. Our work
  spans the continuum from identifying causative variants in rare\, severe 
 infectious conditions to characterizing the genetic architecture underlyin
 g population-level immune variation and common infectious diseases. We've 
 broadened our analytical framework beyond human genomics to incorporate pa
 thogen genetic data\, as well as transcriptomic and metabolomic profiles\,
  capturing the complex dynamics of host-pathogen interactions. Recently\,
  we've implemented AI-based analytical methods to analyze complex pattern
 s within large datasets\, revealing previously undetected associations bet
 ween genetic factors\, biomarkers\, and clinical outcomes. These integrate
 d methodologies are reshaping our understanding of how genetic variation i
 nfluences individual immune signatures and infection susceptibility\, with
  implications for developing targeted preventive strategies and personalis
 ed therapeutic interventions.\n\nBIO\nJacques Fellay is an Associate Profe
 ssor at EPFL and University of Lausanne\, also serving as Director of the 
 CHUV precision medicine unit and as Chief Scientist at the Geneva-based He
 alth 2030 Genome Center. He received his MD from the University of Lausann
 e and his PhD from Utrecht University. After clinical training in internal
  medicine and infectious diseases\, he developed expertise in human genomi
 cs and bioinformatics during his postdoctoral work at Duke University. His
  research focuses on deciphering the molecular foundations of individual v
 ariations in immunity and infection responses\, with the ultimate goal of 
 translating genomic discoveries into clinical applications. During the COV
 ID-19 pandemic\, he provided scientific guidance as a member of the Swiss 
 national COVID-19 science task force and leader of EPFL's COVID scientific
  task force. He received several awards\, including the National Latsis Pr
 ize and the Leenaards Prize for translational medical research.\n\nThis se
 minar is part of the evaluation of Prof Fellay for the promotion to Full P
 rofessor.\n 
LOCATION:SV 1717 https://epfl.zoom.us/j/66115900110
STATUS:CONFIRMED
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