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SUMMARY:EPFL BioE Talks SERIES  "Stem Cell Zoo – Platform to Study Speci
 es-Specific Biological Tempo"
DTSTART:20250512T121500
DTEND:20250512T131500
DTSTAMP:20260916T085033Z
UID:75e99d6be42950b4cf63b241eaec6cd23577c1b52b52f352923dfc90
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Miki Ebisuya\, Physics of Life\, TU Dresden (DE)\nWEEKLY
  EPFL BIOE TALKS SERIES (sandwiches provided)\n\nAbstract:\nDifferent anim
 al species operate at distinct biological tempos. Our group investigates t
 he mechanisms underlying species-specific biological tempo using stem cell
 -based in vitro models.\nSo far\, we have successfully recaplitulated the 
 segmentation clock—oscillatory gene expression during early development
 —using pluripotent stem cells from six mammalian species\, including hum
 an\, mouse\, marmoset\, and rhinoceros. Our findings indicate that these d
 ifferences arise from variations in the kinetics of the segmentation clock
  mechanism\, including species-specific protein degradation rates and dela
 ys in gene expression processes. Moreover\, we have shown that several met
 abolic inhibitions selectively impact these kinetics.\nExpanding our explo
 ration of biological tempo\, we are now studying species-specific heart ra
 tes by deriving cardiac pacemaker cells from our stem cell zoo.\n\n\nBio:\
 nEducation:\n  2003–2008: Graduate School of Biostudies\, Kyoto Univers
 ity (Dr. Eisuke Nishida lab) – Ph.D.\n  1999–2003: Faculty of Science
 \, Kyoto University – B.Sc.\n\nScientific Career:\n  2023–current\n 
  Alexander von Humboldt Professor\, Chair of Cell and Tissue Control\, Clu
 ster of Excellence Physics of Life\, TU Dresden\, Germany\n  2018–2025\
 n  Group Leader at EMBL Barcelona\, Spain (2023-2025 Visiting Group Leade
 r)\n  2013–2019\n  Unit Leader\, RIKEN\, Japan\n  2009–2013\n  Gro
 up Leader\, Career-Path Promotion Unit\, Kyoto University\, Japan\n  2008
 \n  PhD\, Kyoto University\, Japan.\n\n\n\nZoom link (with one-time regis
 tration for the whole series) for attending remotely: https://go.epfl.ch/E
 PFLBioETalks\n\n\nInstructions for 1st-year Ph.D. students planning to att
 end this talk\, who are under EDBB’s mandatory seminar attendance rule:\
 nIN CASE you cannot attend in-person in the room\, please make sure to\n\n
 	send D. Reinhard a note well ahead of time (ideally before seminar day)\,
  informing that you plan to attend the talk online\, and\, during seminar:
 \n	be signed in on Zoom with a recognizable user name (not any alias makin
 g it difficult or impossible to identify you).\n\nStudents attending the s
 eminar in-person should collect a confirmation signature after the talk - 
 please print your own signature sheet beforehand (69 kB pdf available for 
 download here). IMPORTANTLY: hang on to this sheet as no signature record 
 is being kept by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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