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SUMMARY:Imaging Seminar: Towards truly quantitative cellular ultrastructur
 e with volume EM and AI
DTSTART:20251112T170000
DTEND:20251112T180000
DTSTAMP:20260526T053522Z
UID:2369d7964205c23f0b3f1988751603abca6ae21b3894d94190423567
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Kedar Narayan\, National Cancer Institute\, NIH\, USA\nJoin
 t seminar with the Dubochet Center for Imaging\, BioImaging and Optics Pl
 atform and BioEM Facility. \n\nAbstract: Electron microscopy (EM) has 
 long been the gold standard for high resolution imaging of cellular ultras
 tructure. Recent advances have extended EM to the third dimension\, allowi
 ng “volume EM” to emerge as an exciting avenue to explore previously i
 naccessible questions in biology\, especially when combined with correlati
 ve methods. In spite of these developments\, volume EM has remained a most
 ly descriptive science\, with a major hurdle being routine and large-scale
  segmentation of features of interest from ever-growing image volumes. The
  current artificial intelligence (AI) revolution has benefited research in
  this space\, with several approaches showing promise when applied to 2D a
 nd 3D EM data. Here I discuss recent work from the wet and dry lab sides o
 f my group: I show examples of new biology revealed simply by imaging cell
 s and tissue in 3D\, and I share our latest AI based solutions to segment 
 large numbers of organelles from these data. These advances open the door 
 to quantitative and statistically robust ultrastructural studies in cell b
 iology.\n\nBio: Kedar Narayan leads the CCR volume EM (CvEM) group. He ha
 s a Ph.D. in immunology and a background in chemistry\, pathology\, biophy
 sics and software engineering. Kedar’s work focuses on developing emergi
 ng technologies for cellular imaging and deploying them to drive collabora
 tive projects. At CvEM\, these include FIB-SEM\, array tomography\, electr
 on tomography and correlative imaging\, as well as powerful AI-based compu
 tational strategies.\n\nThe seminar is followed by an aperitif. \n\nRegis
 tration appreciated\nLook at our other events here
LOCATION:BM 5202 https://plan.epfl.ch/?room==BM%205202
STATUS:CONFIRMED
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