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VERSION:2.0
PRODID:-//Memento EPFL//
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SUMMARY:EPFL BioE Talks SERIES  "Optical\, Thermal\, and Autonomous Contro
 l of Protein Condensation  And Cell Behavior"
DTSTART:20251027T121500
DTEND:20251027T131500
DTSTAMP:20260527T162758Z
UID:a98daf67e56df8ea9a0a614420844c27773474832a36a02b91fd0ccb
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Lukasz Bugaj\, Department of Bioengineering\, Universit
 y of Pennsylvania\, Philadelphia\, PA (USA)\nWEEKLY EPFL BIOE TALKS SERIE
 S (sandwiches provided)\n\nAbstract:\nRemote-controllable proteins allow a
  high-resolution understanding of cell regulation through space and time. 
 I will highlight our recent discovery of a fungal protein that responds to
  both light and temperature and our efforts to engineer these responses fo
 r an array of new molecular probes\, with particular focus on purely tempe
 rature-sensitive proteins for control of cells deep within opaque animal t
 issues. I will also describe our recent development of the CluMPS\, a fluo
 rescent biosensor of small protein complexes that would otherwise fall bel
 ow the detection threshold of light microscopy. I will show how CluMPS rev
 ealed the unexpected presence and dynamics of protein assemblies that driv
 e cancer and the cell stress response.\n\n\nBio:\nLukasz Bugaj is an Assis
 tant Professor in Bioengineering. He earned his BSE in Biomedical Engineer
 ing at Johns Hopkins University. He then earned his Ph.D. in Bioengineerin
 g with David Schaffer at Berkeley\, where he pioneered some of the first m
 ethods for light-activated 'optogenetic' control of mammalian cell signali
 ng. He then completed a postdoctoral fellowship with Wendell Lim at UCSF\,
  where he applied optogenetic technology to uncover functional signaling d
 efects in cancer cells. The Bugaj Lab at Penn combines optogenetics and sy
 nthetic biology to understand and engineer biological control\, including 
 within therapeutic cells.\n\n\nZoom link (with one-time registration for t
 he whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks\
 n\n\nInstructions for 1st-year Ph.D. students planning to attend this talk
 \, who are under EDBB’s mandatory seminar attendance rule:\nIN CASE you 
 cannot attend in-person in the room\, please make sure to\n\n	send D. Rein
 hard a note well ahead of time (ideally before seminar day)\, informing th
 at you plan to attend the talk online\, and\, during seminar:\n	be signed 
 in on Zoom with a recognizable user name (not any alias making it difficul
 t or impossible to identify you).\n\nStudents attending the seminar in-per
 son should collect a confirmation signature after the talk - please print 
 your own signature sheet beforehand (69 kB pdf available for download here
 ). IMPORTANTLY: hang on to this sheet as no signature record is being kept
  by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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