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SUMMARY:EPFL BioE Talks SERIES "Mobility-Induced Synchronization and Fluct
 uation in Developmental Patterns"
DTSTART:20260330T121500
DTEND:20260330T131500
DTSTAMP:20260415T081419Z
UID:ecb3d96c96c21f4117f4a30cc4aa2b7914f72e02a8c253106d7cff69
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Koichiro Uriu\, School of Life Science and Technology\,
  Institute of Science Tokyo (JPN)\nWEEKLY EPFL BIOE TALKS SERIES (sandwich
 es provided)\n\nAbstract:\nCell movement plays a pivotal role in morphogen
 esis during development. By causing cell rearrangement\, cell mobility ind
 uces fluctuations in developmental patterns. However\, such rearrangements
  may also impact intercellular communication\, promoting information trans
 fer in tissues. In this presentation\, I present a theoretical framework t
 o analyze the effects of cell mobility on developmental patterns. First\, 
 I will show how developmental patterns generated by a morphogen gradient f
 luctuate due to cell movement. Potential mechanisms that minimize these mo
 bility-induced fluctuations are discussed. Second\, I will show that cell 
 mobility can promote synchronization of the segmenting clock\, gene expres
 sion rhythms which determine the timing of body segment formation in verte
 brates. Finally\, I will show that the impact of cell mobility on developm
 ental patterns depends on the pattern wavelength. This theoretical framewo
 rk paves the way for exploring how precise patterning is achieved within d
 ynamic tissues.\n\nBio:\nKoichiro Uriu received his B.S. from the Departme
 nt of Biology at Niigata University and his Ph.D. in Mathematical Biology 
 from Kyushu University\, Japan. He served as a Postdoctoral Research Fello
 w of the Japan Society for the Promotion of Science (JSPS) and joined the 
 research group of Dr. Andrew Oates at the Max Planck Institute of Molecula
 r Cell Biology and Genetics in Dresden. In 2012\, he joined the Theoretica
 l Biology Laboratory at RIKEN as a postdoctoral researcher. During this pe
 riod\, he developed a theoretical framework for the synchronization of mob
 ile oscillators and applied it to genetic oscillators in vertebrate somito
 genesis. He was appointed Assistant Professor at Kanazawa University in 20
 15\, where he initiated research on mammalian circadian clocks. In 2023\, 
 he joined the Tokyo Institute of Technology (now Institute of Science Toky
 o) as an Associate Professor. The Uriu Lab currently focuses on biological
  rhythms\, utilizing mathematical modeling and simulations to uncover the 
 mechanisms of temporal and spatial coordination in living systems.\n\nZoom
  link (with one-time registration for the whole series) for attending remo
 tely: https://go.epfl.ch/EPFLBioETalks\n\n\nInstructions for 1st-year Ph.D
 . students planning to attend this talk\, who are under EDBB’s mandatory
  seminar attendance rule:\nIN CASE you cannot attend in-person in the room
 \, please make sure to\n\n	send Fiorella Ghisays a note well ahead of ti
 me (ideally before seminar day)\, informing that you plan to attend the ta
 lk online\, and\, during seminar:\n	be signed in on Zoom with a recognizab
 le user name (not any alias making it difficult or impossible to identify 
 you).\n\nStudents attending the seminar in-person should collect a confirm
 ation signature after the talk - please print your own signature sheet bef
 orehand (69 kB pdf available for download here). IMPORTANTLY: hang on to t
 his sheet as no signature record is being kept by anyone else!
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://go.epfl.ch/
 EPFLBioETalks
STATUS:CONFIRMED
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