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SUMMARY:Design and Application of New Pericyclic Strategies
DTSTART:20260213T160000
DTEND:20260213T170000
DTSTAMP:20260921T144553Z
UID:65a92ee926dd05f7ec443c912da538e300f80bbf1fb0ba7245084a4c
CATEGORIES:Conferences - Seminars
DESCRIPTION:Christopher Newton\, Assistant Professor at the  Department 
 of Chemistry\, University of Georgia\, USA\nThe overarching theme of our r
 esearch program concerns the development of new and general pericyclic str
 ategies that enable efficient access to complex cyclic frameworks of biolo
 gical importance. A hallmark of our approach is the design of atypical cyc
 loaddition reaction partners that are at a high oxidation level (i.e.\, la
 rge degree of heteroatom incorporation and/or unsaturation) in order to co
 nfer unique reactivity\, while also minimizing the need for redox manipula
 tions post cycloaddition. A significant challenge within this area is the 
 development of methods that remain operationally friendly\, for highly uns
 aturated heteroatom-rich molecules often exhibit challenging stability pro
 files. Generally speaking\, our approaches leverage fundamental structure 
 and reactivity studies to inform the optimization of our proposed reaction
  partners in order to gain kinetic stability without sacrificing desired r
 eactivity. Once we have developed a new methodology\, our focus pivots tow
 ard applications in target-oriented synthesis\, typically merging our abio
 tic pericyclic methodologies with bioinspired cascades.\n 
LOCATION:Unil - Génopod A https://plan.epfl.ch/?room==BCH%202201
STATUS:CONFIRMED
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