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SUMMARY:BMI Seminar // Jeff Holt: Function\, Dysfunction and Restoration o
 f Auditory Sensory Transduction
DTSTART:20260306T140000
DTEND:20260306T150000
DTSTAMP:20260413T104949Z
UID:e026d30bf41264e516a105a3df5104310b0999939cbe5beaf1a84908
CATEGORIES:Conferences - Seminars
DESCRIPTION:Jeff Holt\, Harvard  University\nThe sensory cells of the in
 ner ear convert sound information into electrical signals that are transmi
 tted to the brain.  A key molecule for this process is a mechanosensitive
  ion channel known as Transmembrane Channel One (TMC1).  TMC1 forms the p
 ore of mechanosensory transduction channels in auditory hair cells.  Over
  a hundred genetic mutations have been identified in the TMC1 gene that ca
 use hearing loss in humans.  To treat patients with TMC1 mutations we hav
 e developed gene replacement\, gene editing and other novel strategies tha
 t restore auditory function in mice.  Our goal is to translate TMC1 thera
 pies and other hearing loss therapies into clinical application. \n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/64813563657
STATUS:CONFIRMED
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