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SUMMARY:Can effector T lymphocytes initiate cancer?
DTSTART:20260529T133000
DTEND:20260529T143000
DTSTAMP:20260404T063253Z
UID:ee244d25037770f806c50960eb64325c14e30f7d9c7176d2123cfe53
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Julien MARIE\, CRCL : Cancer Research Center of Lyon \n
 Abstract\nAround 30% of cancers are preceded by chronic inflammation which
  occurs at the site where tumors will develop. However\, whether this onco
 genic process\, particularly observed in the intestine\, can be initiated 
 by a specific immune cell population remains unknown. We recently identifi
 ed two distinct effector T cell populations capable to initiate the oncoge
 nic transformation of a healthy intestinal epithelium (Fesneau et al.\, Na
 t Immunol. 2024\; Brewer et al.\, Nat. Rev. Canc. 2024)\, as well as the f
 actors controlling their differentiation. By revealing the presence of tu
 morigenic T cells\, this work opens a new field in oncology and immunology
  that will be key for both our understanding of the early steps of carcin
 ogenesis and the development of prophylactic therapies against cancer.\n\
 n\n\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/65172501275
STATUS:CONFIRMED
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