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SUMMARY:Ecological Engineering of the Intestinal Microbiome
DTSTART:20260427T121500
DTEND:20260427T131500
DTSTAMP:20260524T234140Z
UID:5b46805df9e3670f93760b39e060c3169d01f085a8458fe747c055cf
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Dr. Médéric Diard\, Basel University\, Biozentrum\nEP
 FL BIOE TALKS SERIES (sandwiches provided)\n\nAbstract:\nThe intestinal m
 icrobiota represents an important line of defense against pathogenic micro
 bes. It is also the most complex microbial community in the human body sha
 ped by multiple host specific factors including diet\, genetic background 
 and environment. Improving the composition of the intestinal microbiota to
  exclude pathogens or to implement therapeutic functions is therefore part
 icularly challenging and remains an unmet medical need. My group studies t
 he ecological forces at play in the intestinal microbiome (i.e.\, the host
  and its microbiota) in health and disease. From this we develop novel mic
 robiome engineering approaches to exclude pathogens. I will present recent
  work showing that combining engineered niche competitors with bacteriopha
 ges and vaccination can strengthen the protective role of the microbiota a
 gainst pathogens and enable robust strain replacement.\n\nBio:\nMédéric 
 Diard's work lies at the intersection of ecology\, evolution\, and microbi
 ology. He obtained his doctorate in microbiology from Paris Diderot Univer
 sity (2008) where he specialized in the evolutionary dynamics of pathogeni
 c enterobacteria. Before taking up his current position\, he was a lecture
 r at ETH Zurich in the Department of Biology (Hardt Group)\, and studied t
 he intra-host evolution of Salmonella Typhimurium. Appointed SNSF professo
 r in 2018 at the Biozentrum of the University of Basel\, Médéric current
 ly leads a research team studying the evolution of gut pathobionts under t
 he selective pressures exerted by the microbiota\, bacteriophages\, and va
 ccines. His work\, funded by an ERC Consolidator grant\, is essential for 
 understanding the evolution of gut pathobionts and strategies for combatin
 g them without relying exclusively on traditional antibiotics.\n\n\nZoom l
 ink (with one-time registration for the whole series) for attending remot
 ely: https://go.epfl.ch/EPFLBioETalks\n\n\nInstructions for 1st-year Ph.D
 . students planning to attend this talk\, who are under EDBB’s mandatory
  seminar attendance rule:\nIN CASE you cannot attend in-person in the room
 \, please make sure to\n\n	send Fiorella Ghisays a note well ahead of ti
 me (ideally before seminar day)\, informing that you plan to attend the ta
 lk online\, and\, during seminar:\n	be signed in on Zoom with a recognizab
 le user name (not any alias making it difficult or impossible to identify 
 you).\n\nStudents attending the seminar in-person should collect a confirm
 ation signature after the talk - please print your own signature sheet bef
 orehand (69 kB pdf available for download here). IMPORTANTLY: hang on to t
 his sheet as no signature record is being kept by anyone else!\n 
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 l.ch/EPFLBioETalks
STATUS:CONFIRMED
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