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SUMMARY:Bioengineering Seminar - Professor Jing Yan - Single-cell Imaging 
 of Microbial Communities across Different Spatial and Temporal Scales
DTSTART:20260612T130000
DTEND:20260612T140000
DTSTAMP:20260524T043752Z
UID:bf12d34a176f1be65cfabd2481282f3ca7bca29829e49e25d4f0e8ab
CATEGORIES:Conferences - Seminars
DESCRIPTION:Professor Jing Yan\, Assistant Professor\, Molecular\, Cellul
 ar and Developmental Biology\, Yale University\nBiofilm is an important li
 festyle of bacteria where bacterial cells collectively form surface-associ
 ated aggregates embedded in a polymeric matrix they secrete. Important in 
 industry and medicine\, biofilms also represent a unique form of growing a
 ctive matter with unique physical and material properties. In this talk\, 
 I will highlight our recent work on developing a platform for imaging live
 \, growing biofilm at single-cell resolution\, using Vibrio cholerae as 
 the model organism. I will show how bacterial cells physically communicate
  with each other and the environment to form ordered architecture reminisc
 ent of  liquid crystals. Moreover\, I will talk about our recent discover
 y that heterogeneity in gene expression leads to unexpected pattern format
 ion in biofilm through a drag-based sorting mechanism. I will also highlig
 ht ongoing research in the lab on extending the imaging capability to more
  natural environments including marine animal hosts. I will end by showing
  our recent findings on the mechanical properties of the extracellular mat
 rix that underlie the architecture of the biofilm.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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