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SUMMARY:EPFL BioEngineering Talks
DTSTART:20261130T121500
DTEND:20261130T131500
DTSTAMP:20260923T081515Z
UID:35da4417b8f60745ec98069dae06f6612ea1dfa6bd655fc4d474086b
CATEGORIES:Conferences - Seminars
DESCRIPTION:Invited Speaker and Student Speaker\nWeekly BioEngineering Tal
 ks ( Lunch Provided)\n\nINVITED SPEAKER:\n\nA full-stack viral toolkit for
  systems neuroscience\nProf. Lief Fenno\, University of Basel Biozentrum
 \n\nAbstract:\n Understanding and manipulating neural circuits requires t
 echnologies enabling access to specific cells\, manipulation of genome str
 ucture\, and delivery of increasingly complex genetic programs. I will des
 cribe viral technologies developed by my group that address each of these 
 challenges. These include INTRSECT\, a Boolean viral targeting strategy fo
 r cell-type- and circuit-specific access\; VESPA\, a novel split-AAV platf
 orm that enables efficient reassembly and expression of genetic payloads t
 oo large for a single AAV\; and CRISPR/Cas9-based strategies for precise\,
  cell-type- and circuit-specific gene knockdown. Together\, these tools fo
 rm an integrated viral toolkit for programmable access to and manipulation
  of neural circuits across multiple levels of biological complexity.\n\nBi
 o:\nDr. Lief Fenno is a physician-scientist at The University of Texas at 
 Austin and Dell Medical School. His research integrates systems neuroscien
 ce\, synthetic biology\, and bioengineering to develop genetic\, viral\, a
 nd neuromodulation technologies for programmable control of neural circuit
 s in vivo. His laboratory develops molecular and viral platforms for selec
 tively accessing and manipulating defined neural populations\, alongside a
 pproaches for neural stimulation and emerging therapeutic applications. Hi
 s work spans fundamental circuit neuroscience\, neurotechnology\, and the 
 translation of biological tools to treatment of brain disorders. Dr. Fenno
  is also a board-certified addiction psychiatrist\, Chair of the American 
 Psychiatric Association Council on Addiction Psychiatry\, and is active in
  commercial scientific translation and biotechnology innovation.\n\nSTUDEN
 T SPEAKER:\n\nTBD\n\n-----------------------------------------------------
 --------------------\n\nBioEngineering Talks mandatory EDBB Seminar Attend
 ance (1st-Year PhD Students)\n\n	 Attendance sheet to print HERE \n\nThe
  BioEngineering Student Seminar Series is an official course for which stu
 dents can register and earn credits\n \n\n	Register HERE\n	Attendance she
 et to print HERE\n\nGeneral information:\nIn-person attendance is preferre
 d to support your fellow students. Zoom is mainly for students on remote c
 ampuses\; please notify Fiorella Ghisays in advance and join using your fu
 ll name.\nIf attending in person\, have your sheet signed after the talk a
 nd keep the original\, as no copy is retained.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/68746410793
STATUS:CONFIRMED
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