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PRODID:-//Memento EPFL//
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SUMMARY:EPFL BioEngineering Talks
DTSTART:20261102T121500
DTEND:20261102T134500
DTSTAMP:20261007T034752Z
UID:f03abb86d5d296bfc173573b67211d07715e9d1850d891a452f51c0b
CATEGORIES:Conferences - Seminars
DESCRIPTION:Invited Speaker and Student Speaker\nWeekly BioEngineering Tal
 ks (Lunch Provided)\n\nINVITED SPEAKER:\nFrom single-molecule biophysics w
 ith Graphene Energy Transfer to Brownian DNA computing\nProf. Dr. Philip T
 innefeld\, LMU Munich\nHost: Prof. Aleksandra Radenovic\n\nAbstract:\nGr
 aphene-on-glass coverslips are an emerging microscopy platform as resonant
  energy transfer to graphene offers an axial ruler in the 5-40 nm range. I
  present single molecule biophysics experiments of protein/DNA interaction
 s using Graphene Energy Transfer (GET) in combination with the discovery t
 hat dsDNA adopts a vertical orientation on graphene. Axial information of 
 DNA structure and protein positions is deduced from GET-efficiency and xy-
 information is obtained e.g. by photon-efficient pMINFLUX revealing simult
 aneous bending and torsion of enzyme induced DNA conformations. Finally\, 
 I discuss how multi-color smFRET with dark quenchers probes states of DNA 
 nanorobots and Brownian DNA computers that work close to the thermodynamic
  optimum.\n\nBio:\nPhilip Tinnefeld is a Professor of Physical Chemistry a
 t Ludwig-Maximilians-Universität München\, leading a highly interdiscipl
 inary NanoBioSciences research group that brings together molecular biolog
 y\, biophysics\, nanophotonics\, and physical chemistry. He specialises in
  single-molecule detection and super-resolution microscopy\, and he uses D
 NA origami to build modular nanoscale devices—such as force sensors\, fl
 uorescence amplifiers\, and molecular robots—that can sense\, compute\, 
 and respond autonomously. Under his leadership\, the lab is also developin
 g advanced biosensing platforms and imaging tools by combining DNA nanotec
 hnology with 2D materials like graphene\, pushing the frontiers of how we 
 observe and control biological processes at the molecular level.\n\nSTUDEN
 T SPEAKER:\n\nUnderstanding oxidative stress response in animals - a case 
 study of the essential enzyme adenosylhomocysteinase\, AHCY\nYong-Qi Gao\,
  Zenk Lab\n\n\n----------------------------------------------------------
 --------------------\n\nBioEngineering Talks mandatory EDBB Seminar Attend
 ance (1st-Year PhD Students)\n\n	 Attendance sheet to print HERE \n\nThe
  BioEngineering Student Seminar Series is an official course for which stu
 dents can register and earn credits.\n \n\n	Register HERE\n	Attendance sh
 eet to print HERE\n\nGeneral information:\nIn-person attendance is preferr
 ed to support your fellow students. Zoom is mainly for students on remote 
 campuses\; please notify Fiorella Ghisays in advance and join using your f
 ull name.\nIf attending in person\, have your sheet signed after the talk 
 and keep the original\, as no copy is retained.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/68746410793
STATUS:CONFIRMED
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