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SUMMARY:Sirtuins and NAD metabolism:  Chemistries and new targets for ther
 apeutics
DTSTART:20110902T133000
DTSTAMP:20260924T205853Z
UID:893b473d629382d9f8ee3a5450e637464b22801c7940e1536e88a8d1
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Anthony Sauve Associate Professor of Pharmacology\, Weill 
 Cornell College of Medicine\, New York City\, NY\, USA\nNAD is a fundament
 al biological cofactor that is central to metabolic transformations and to
  energy homeostasis.  Signaling enzymes such as sirtuins\, which use NAD a
 s a substrate\, are regulated by dynamic fluctuations in NAD and nicotinam
 ide levels in cells\, thereby controlling fundamental processes such as st
 ress resistance\, DNA repair and metabolic reprogramming.  The Sauve labor
 atory investigates the chemistries of NAD and sirtuins in detail and devel
 ops novel chemical tools to manipulate these targets in cells.  One eventu
 al aim is to develop new approaches to alter cell and tissue biology for t
 herapeutic benefit.  
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
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