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VERSION:2.0
PRODID:-//Memento EPFL//
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SUMMARY:DNA Sequencing by Tunneling  (joint Electrical Engineering & Bioen
 gineering seminar)
DTSTART:20130527T151500
DTEND:20130527T161500
DTSTAMP:20260916T050047Z
UID:feddc733cd9a4e6e34d0d29396928ff39194f5b0813cea95baa76bf7
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Massimiliano Di Ventra\, Department of Physics\, Univers
 ity of California San Diego\, La Jolla\, CA (USA)\nBio: Massimiliano Di Ve
 ntra obtained his undergraduate degree in Physics summa cum laude from the
  University of Trieste (Italy) in 1991 and did his PhD studies at the Ecol
 e Polytechnique Federale de Lausanne (Switzerland) in 1993-1997. He has be
 en Research Assistant Professor at Vanderbilt University and Visiting Scie
 ntist at IBM T.J. Watson Research Center before joining the Physics Depart
 ment of Virginia Tech in 2000 as Assistant Professor. He was promoted to A
 ssociate Professor in 2003 and moved to the Physics Department of the Univ
 ersity of California\, San Diego\, in 2004 where he was promoted to Full P
 rofessor in 2006. Di Ventra's research interests are in the theory of elec
 tronic and transport properties of nanoscale systems\, non-equilibrium sta
 tistical mechanics\, DNA sequencing/polymer dynamics in nanopores\, and me
 mory effects in nanostructures for applications in unconventional computin
 g and biophysics. He has been invited to deliver more than 170 talks world
 wide on these topics. He serves on the editorial board of several scientif
 ic journals and has won numerous awards and honors\, including the NSF Ear
 ly CAREER Award\, the Ralph E. Powe Junior Faculty Enhancement Award\, fel
 lowship in the Institute of Physics and the American Physical Society. He 
 has published more than 140 papers in refereed journals (12 of these are l
 isted as ISI Essential Science Indicators highly-cited papers of the perio
 d 2002-2012)\, co-edited the textbook Introduction to Nanoscale Science an
 d Technology (Springer\, 2004) for undergraduate students\, and he is sing
 le author of the graduate-level textbook Electrical Transport in Nanoscale
  Systems (Cambridge University Press\, 2008).\n“Personalized medicine”
  refers to the ability of tailoring drugs to the specific genome of each i
 ndividual [1]. It is however not yet feasible due the high cost and slow s
 peed of present DNA sequencing methods. I will discuss a DNA sequencing pr
 otocol we suggest that requires the measurement of the distributions of tr
 ansverse currents during the translocation of single-stranded DNA into nan
 opores [2-5]. I will show that such a sequencing approach can reach unprec
 edented speeds\, thus opening up the possibility for personalized medicine
 . I will also discuss recent experiments that support these theoretical pr
 edictions and are a step forward toward making personalized medicine a rea
 lity [6].References\n1. M. Zwolak\, M. Di Ventra\, Rev. Mod. Phys. 2008\, 
 80\, 141.\n2. M. Zwolak and M. Di Ventra\, Nano Lett. 5\, 421 (2005).\n3. 
 J. Lagerqvist\, M. Zwolak\, and M. Di Ventra\, Nano Lett.\, 2006 6\, 779.\
 n4. J. Lagerqvist\, M. Zwolak\, and M. Di Ventra\, Biophys. J. 2007\, 93\,
  2384.\n5. M. Krems\, M. Zwolak\, Y.V. Pershin\, and M. Di Ventra\, Biophy
 s. J. 2009\, 97\, 1990.\n6. T. Ohshiro\, K. Matsubara\, M. Tsutsui\, M. Fu
 ruhashi\, M. Taniguchi and T. Kawai\, Nature: Scientific Reports\, 2012\, 
 2\, 501.
LOCATION:SV1717a http://map.epfl.ch/?room=sv1717a
STATUS:CONFIRMED
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