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SUMMARY:Leveraging Moment-to-Moment Brain Signal Variability in the Examin
 ation of Human Aging and Cognition
DTSTART:20130703T101500
DTEND:20130703T111500
DTSTAMP:20260428T162716Z
UID:177ac90aeef1be4fffc3fedd9d5052161406b9d6901c98145488919b
CATEGORIES:Conferences - Seminars
DESCRIPTION:Douglas D. Garrett\, Ph.D.\, Max Planck Institute for Human De
 velopment\, Berlin (D)\nBio: M.A./Ph.D. Psychology\, 2005 - 2011\n    
 ✦Cognitive Neuroscience of Aging\n    ✦Department of Psychology\, U
 niversity of Toronto\, & Rotman Research Institute\, Toronto\, ON\nB.A. (H
 onours) Psychology\, 1998 - 2003\n    ✦Honours\, Co-Op\, with Distinc
 tion\n    ✦Department of Psychology\, University of Victoria\, Victor
 ia\, BC\nNeuroscientists have long observed that brain activity is natural
 ly variable from moment-to-moment\, yet neuroimaging research has rarely c
 onsidered signal variability as a within-person measure of interest. Our f
 MRI work on younger and older adults suggests that within-person BOLD sign
 al variability offers highly predictive\, complementary\, and even orthogo
 nal views of brain function compared to traditional mean-based measures. I
 n particular\, we continue to find that older\, poorer performing adult br
 ains often exhibit less signal variability\, within and across brain regio
 ns and tasks. Accordingly\, I will discuss the idea that contrary to tradi
 tional theoretical expectations of adult-developmental increases in "neura
 l noise\," brain aging could instead be re-conceived of as a generalized p
 rocess of increasing system rigidity and loss of dynamic range.
LOCATION:SV1717a http://map.epfl.ch/?room=sv1717a
STATUS:CONFIRMED
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